Default Cytomegalovirus infection (CMV) induces clinical syndrome which is usually associated with hearing loss. However, the effect of CVM infection obtained in adults and children has not been clearly defined. The purpose of this review is to critically assess the scientific evidence of the Association of CMV infection obtained by postnatal or tinnitus hearing loss. Systematic Overview of Records Reporting Sensorineural Loss (SNHL) or Tinnitus and CMV infection obtained including articles published in English is done.

The search strategy is limited to human studies with CMV infection obtained. After screening and quality assessment, nine studies involving 1528 individuals meet inclusion criteria. A total of 14% of patients with SNHL showed evidence of previous exposure to CMV, while in individuals without SNHL (control) percentage rose to 19.3%. SNHL was reported as unilateral or bilateral at 15.3%, and was not determined in 84.7% of cases. SNHL levels range from mild to deep for children and adults. None of the records reported by Tinitus.

The prevalence of children or adults with SNHL acquired by CMV infection obtained confirmed by polymerase chain reaction (PCR) or low IgM anti-CMV antibodies. Fenotyping of patients with CMV infection obtained is limited to hearing loss with pure tone audiometry and no additional audiological tests carried out in most studies. Additional symptoms deserve more attention, including vertigo episodic or tinnitus, because some patients with the clinical spectrum of meniere disease can result from a latent infection of CMV.

Nitrate oxide flows metabolic regulations mediated by a virus during human cytomegalovirus infection

Nitric Oxide is a multipurpose and critical effector molecule that can modulate many cellular functions. Although it is recognized as a regulator of infection, the inhibition mechanism of nitric oxide on human cytomegalovirus replication (HCMV) is still difficult to understand. We show that nitric oxide weakens viral replication by disrupting modulation mediated by HCMV from several cellular processes.

Nitric oxide exposure reduces the synthesis of HCMV genomes and offspring virus infections with differences depending on the type of cell. Mitochondrial respiration greatly reduced both in infected and infected cells HCMV during exposure with a slight impact at the ATP level which shows changes in cellular metabolism. Metabolomics identifies small molecules that change significantly in several routes during exposure to nitrate oxide including nucleotide biosynthesis, tricarboxylic acid cycles (TCA), and glutamine metabolism. Glutathione metabolites increased to coincide with the reduction of glutamine precursor glutathione.

This shift is accompanied by an increase in antioxidant enzymes. Glutamine deprivation imitated defects in HCMV replication and mitochondrial respiration observed during exposure to nitrate oxide. This data shows that nitric oxide limits glutamineolysis by diverting glutamine to glutathione synthesis. In addition, lipid intermediaries are challenuous, which is likely to contribute to the increase in virus particles observed. Nitric Oxide interferes with several cellular processes, and we have limited success in saving defects replication by adding metabolic intermediaries. Our studies show that the ace of nitrate oxide from HCMV is multifactorial with interference with cellular metabolic viruses that play a central role. The importance of human cytomegalovirus is a common pathogen in patients with a compromised immune system, including transplant patients and during innate infections. Lytic HCMV replication is likely to occur on local infection sites with immune cells that infiltrate and release nitrate oxide with other effector molecules.

The clinical results of the recipients of alogenic hematopoietic stem cell transplants develop DNAEMIA CYTOMEGALOVIRUS before the endraftment

There is limited information about the impact of DNAEMIA CMV episodes that develop before the endraftment (pre-cmv dnaemia) in clinical results after alogenic hematopoietic stem cell transplantation (allo-HSCT). This problem is intended for retrospective multicenter studies currently including 878 patients. All participating centers use the preemptive antivirus therapy strategy for prevention of CMV disease. The load of CMV DNA in the blood is monitored by a real-time PCR test. A total of 144 patients (cumulative events were 16.5%, 95% CI, 14% -19%) had a pre-CMV dnaemia episode on the median 10 days after allo-HSCT.

Patients who develop pre-CMV Dnaemia have a significant probability of recurrent episodes (P = <0.001) (50%) than those who experience post-CMV dnaemia (32.9%); However, the incidence of comparable CMV disease (p = 0.52). The cumulative incidence of the overall death (OM) and non-relapse mortality (NRM) at 1 year after the Allo-HSCT was 32% (95% CI, 29-35%) and 23% (95% CI 20-26%), respectively -Masing. The risk of OM and NRM in a customized model emerged proportion to patients who developed a DNAemia CMV episode, regardless of whether it happened before or after the endraftment, in patients with CMV CMV episodes before and post-engraftment or on those without CMV Dnaemia.

Cytomegalovirus Retinitis After transplantation of alogenic hematopoietic stem cells under the active screening of cytomegalovirus antigenemia

Although Cytomegalovirus (CMV) remains a major cause of morbidity and mortality after transplantation of hematopoietic stem cells (HSCT), the incidence of CMV retinitis is considered lower than the incidence of CMV infection in other organs after the shite. In this study, the incidence and characteristics of CMV retinitis were retrospectively evaluated at the Alogenic HSCT receiver. Eye playback is carried out on the development of ocular symptoms or positive CMV infections using peripheral blood evaluated by antigenemia PP65 or a polymerase chain reaction. Of the 514 patients, 13 patients developed CMV retinitis. The median onset of CMV retinitis is day 34 (range, 21-118) post transplants, and cumulative events are 2.5% (95% CI, 1.6-42) at 6 months after transplantation.

NUMBL Antibody
DF6863-200ul	Affinity Biosciences	200ul	EUR 350

NUMBL Antibody
E92140	EnoGene	100ul	EUR 255
Description: Available in various conjugation types.

NUMBL Antibody
ABD6863	Nova Lifetech	100ug	EUR 325

NUMBL Antibody
R36056-100UG	NSJ Bioreagents	100 ug	EUR 339.15
Description: Additional name(s) for this target protein: Numb-like

NUMBL Antibody
MBS7108731-005mg	MyBiosource	0.05mg	EUR 190

NUMBL Antibody
MBS7108731-01mg	MyBiosource	0.1mg	EUR 270

NUMBL Antibody
MBS7108731-5x01mg	MyBiosource	5x0.1mg	EUR 1205

NUMBL antibody
MBS9406496-005mL	MyBiosource	0.05mL	EUR 300

NUMBL antibody
MBS9406496-01mL	MyBiosource	0.1mL	EUR 390

NUMBL antibody
MBS9406496-5x01mL	MyBiosource	5x0.1mL	EUR 1610

NUMBL Antibody
MBS8516333-01mg	MyBiosource	0.1mg	EUR 305

NUMBL Antibody
MBS8516333-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 465

NUMBL Antibody
MBS8516333-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 465

NUMBL Antibody
MBS8516333-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 465

NUMBL Antibody
MBS8516333-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 465

NUMBL Antibody
MBS8504604-01mL	MyBiosource	0.1mL	EUR 325

NUMBL Antibody
MBS8504604-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 565

NUMBL Antibody
MBS8504604-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 565

NUMBL Antibody
MBS8504604-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 565

NUMBL Antibody
MBS8504604-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 565

NUMBL Antibody
MBS2522682-006mL	MyBiosource	0.06mL	EUR 230

NUMBL Antibody
MBS2522682-012mL	MyBiosource	0.12mL	EUR 310

NUMBL Antibody
MBS9607516-01mL	MyBiosource	0.1mL	EUR 260

NUMBL Antibody
MBS9607516-02mL	MyBiosource	0.2mL	EUR 305

NUMBL Antibody
MBS9607516-5x02mL	MyBiosource	5x0.2mL	EUR 1220

NUMBL Antibody
C45119-100ul	Assay Biotech	100μl	EUR 217
Description: NUMBL Rabbit Polyclonal Antibody

NUMBL Antibody
C45119-50ul	Assay Biotech	50μl	EUR 143.5
Description: NUMBL Rabbit Polyclonal Antibody

anti- NUMBL antibody
FNab05917	FN Test	100µg	EUR 606.3
Description: Antibody raised against NUMBL

anti- NUMBL antibody
FNab05918	FN Test	100µg	EUR 702
Description: Antibody raised against NUMBL

NUMBL Antibody (C-term)
MBS9204395-008mL	MyBiosource	0.08mL	EUR 210

NUMBL Antibody (C-term)
MBS9204395-04mL	MyBiosource	0.4mL	EUR 430

NUMBL Antibody (C-term)
MBS9204395-5x04mL	MyBiosource	5x0.4mL	EUR 1910

NUMBL Antibody, HRP conjugated
1-CSB-PA897595LB01HU	Cusabio	Ask for price Ask for price	100ug 50ug
Description: A polyclonal antibody against NUMBL. Recognizes NUMBL from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

NUMBL Antibody, HRP conjugated
MBS7108732-005mg	MyBiosource	0.05mg	EUR 190

NUMBL Antibody, HRP conjugated
MBS7108732-01mg	MyBiosource	0.1mg	EUR 270

NUMBL Antibody, HRP conjugated
MBS7108732-5x01mg	MyBiosource	5x0.1mg	EUR 1205

NUMBL Antibody, FITC conjugated
1-CSB-PA897595LC01HU	Cusabio	Ask for price Ask for price	100ug 50ug
Description: A polyclonal antibody against NUMBL. Recognizes NUMBL from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

NUMBL Antibody, FITC conjugated
MBS7108733-005mg	MyBiosource	0.05mg	EUR 190

NUMBL Antibody, FITC conjugated
MBS7108733-01mg	MyBiosource	0.1mg	EUR 270

NUMBL Antibody, FITC conjugated
MBS7108733-5x01mg	MyBiosource	5x0.1mg	EUR 1205

NUMBL Antibody, Biotin conjugated
1-CSB-PA897595LD01HU	Cusabio	Ask for price Ask for price	100ug 50ug
Description: A polyclonal antibody against NUMBL. Recognizes NUMBL from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

OAAJ07337-100UL - NUMBL Antibody
OAAJ07337-100UL	Aviva Systems Biology	100uL	EUR 319

NUMBL Antibody, Biotin conjugated
MBS7108734-005mg	MyBiosource	0.05mg	EUR 190

NUMBL Antibody, Biotin conjugated
MBS7108734-01mg	MyBiosource	0.1mg	EUR 270

NUMBL Antibody, Biotin conjugated
MBS7108734-5x01mg	MyBiosource	5x0.1mg	EUR 1205

NUMBL Polyclonal Antibody
A70355	EpiGentek	Ask for price Ask for price Ask for price Ask for price	100 ?g 20 ul 50 ul 100 ul

NUMBL Polyclonal Antibody
E914088	EnoGene	100ul	EUR 225
Description: Available in various conjugation types.

NUMBL Conjugated Antibody
C38379	SAB	100ul	EUR 476.4

NUMBL Polyclonal Antibody
MBS127004-002mL	MyBiosource	0.02mL	EUR 200

NUMBL Polyclonal Antibody
MBS127004-005mL	MyBiosource	0.05mL	EUR 255

NUMBL Polyclonal Antibody
MBS127004-01mL	MyBiosource	0.1mL	EUR 345

NUMBL Polyclonal Antibody
MBS127004-02mL	MyBiosource	0.2mL	EUR 545

NUMBL Polyclonal Antibody
MBS127004-5x02mL	MyBiosource	5x0.2mL	EUR 2265

NUMBL Polyclonal Antibody
MBS9234267-01mL	MyBiosource	0.1mL	EUR 415

NUMBL Polyclonal Antibody
MBS9234267-5x01mL	MyBiosource	5x0.1mL	EUR 1841

NUMBL Polyclonal Antibody
MBS9134097-002mL	MyBiosource	0.02mL	EUR 200

NUMBL Polyclonal Antibody
MBS9134097-005mL	MyBiosource	0.05mL	EUR 255

NUMBL Polyclonal Antibody
MBS9134097-01mL	MyBiosource	0.1mL	EUR 345

NUMBL Polyclonal Antibody
MBS9134097-02mL	MyBiosource	0.2mL	EUR 545

NUMBL Polyclonal Antibody
MBS9134097-5x02mL	MyBiosource	5x0.2mL	EUR 2265

NUMBL Polyclonal Antibody
MBS8568786-01mL	MyBiosource	0.1mL	EUR 305

NUMBL Polyclonal Antibody
MBS8568786-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 565

NUMBL Polyclonal Antibody
MBS8568786-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 565

NUMBL Polyclonal Antibody
MBS8568786-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 565

NUMBL Polyclonal Antibody
MBS8568786-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 565

NUMBL Polyclonal Antibody
MBS2566247-006mL	MyBiosource	0.06mL	EUR 190

NUMBL Polyclonal Antibody
MBS2566247-012mL	MyBiosource	0.12mL	EUR 265

NUMBL Polyclonal Antibody
MBS2566247-02mL	MyBiosource	0.2mL	EUR 415

NUMBL Polyclonal Antibody
MBS2566247-5x02mL	MyBiosource	5x0.2mL	EUR 1835

NUMBL Conjugated Antibody
MBS9448603-01mLAF350	MyBiosource	0.1mL(AF350)	EUR 480

NUMBL Conjugated Antibody
MBS9448603-01mLAF405	MyBiosource	0.1mL(AF405)	EUR 480

NUMBL Conjugated Antibody
MBS9448603-01mLAF488	MyBiosource	0.1mL(AF488)	EUR 480

NUMBL Conjugated Antibody
MBS9448603-01mLAF555	MyBiosource	0.1mL(AF555)	EUR 480

NUMBL Conjugated Antibody
MBS9448603-01mLBiotin	MyBiosource	0.1mL(Biotin)	EUR 480

NUMBL Polyclonal Antibody
RD267415A-120uL	Reddot Biotech	120μL	EUR 360
Description: NUMBL (NUMB Like Endocytic Adaptor Protein) is a Protein Coding gene. Diseases associated with NUMBL include Differentiating Neuroblastoma. Among its related pathways are Notch Signaling Pathway (WikiPathways). An important paralog of this gene is NUMB.

NUMBL Polyclonal Antibody
RD267415A-200uL	Reddot Biotech	200μL	EUR 630
Description: NUMBL (NUMB Like Endocytic Adaptor Protein) is a Protein Coding gene. Diseases associated with NUMBL include Differentiating Neuroblastoma. Among its related pathways are Notch Signaling Pathway (WikiPathways). An important paralog of this gene is NUMB.

NUMBL Polyclonal Antibody
RD267415A-60uL	Reddot Biotech	60μL	EUR 204
Description: NUMBL (NUMB Like Endocytic Adaptor Protein) is a Protein Coding gene. Diseases associated with NUMBL include Differentiating Neuroblastoma. Among its related pathways are Notch Signaling Pathway (WikiPathways). An important paralog of this gene is NUMB.

Polyclonal NUMBL Antibody (N-Term)
AMM06872G	Leading Biology	0.1 mg	EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human NUMBL (N-Term). This antibody is tested and proven to work in the following applications:

Polyclonal NUMBLIKE / NUMBL Antibody (N-Terminus)
AMM06873G	Leading Biology	0.05ml	EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NUMBLIKE / NUMBL (N-Terminus). This antibody is tested and proven to work in the following applications:

NUMBL Antibody (C-term) Blocking peptide
MBS9220443-INQUIRE	MyBiosource	INQUIRE	Ask for price

NUMBL Rabbit Polyclonal Antibody
BT-AP11613-100ul	Jiaxing Korain Biotech Ltd (BT Labs)	100ul	Ask for price

NUMBL Rabbit Polyclonal Antibody
BT-AP11613-20ul	Jiaxing Korain Biotech Ltd (BT Labs)	20ul	Ask for price

NUMBL Rabbit Polyclonal Antibody
BT-AP11613-50ul	Jiaxing Korain Biotech Ltd (BT Labs)	50ul	Ask for price

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx117223-100ug	Abbexa	100 ug	EUR 560.4

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
20-abx001752	Abbexa	Ask for price Ask for price Ask for price Ask for price	100 ul 200 ul 20 ul 50 ul

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx235917-100ug	Abbexa	100 ug	EUR 577.2

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx235918-100ug	Abbexa	100 ug	EUR 661.2

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
20-abx334204	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 1 mg 200 ug 20 ug 50 ug

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx431475-200ul	Abbexa	200 ul	EUR 460.8

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx117223-100g	Abbexa	100 µg	EUR 450

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx235917-100g	Abbexa	100 µg	EUR 350

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx235918-100g	Abbexa	100 µg	EUR 350

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx431475-200l	Abbexa	200 µl	EUR 387.5

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx433691-100g	Abbexa	100 µg	EUR 387.5

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx334204-100g	Abbexa	100 µg	EUR 362.5

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx334204-20g	Abbexa	20 µg	EUR 162.5

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx334204-50g	Abbexa	50 µg	EUR 250

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx001752-100l	Abbexa	100 µl	EUR 387.5

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx001752-20l	Abbexa	20 µl	EUR 175

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody
abx001752-50l	Abbexa	50 µl	EUR 275

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (HRP)
20-abx336868	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 1 mg 200 ug 20 ug 50 ug

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (HRP)
abx336868-100g	Abbexa	100 µg	EUR 362.5

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (HRP)
abx336868-20g	Abbexa	20 µg	EUR 162.5

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (HRP)
abx336868-50g	Abbexa	50 µg	EUR 250

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (FITC)
20-abx336869	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 1 mg 200 ug 20 ug 50 ug

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (FITC)
abx336869-100g	Abbexa	100 µg	EUR 362.5

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (FITC)
abx336869-20g	Abbexa	20 µg	EUR 162.5

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (FITC)
abx336869-50g	Abbexa	50 µg	EUR 250

NUMBL Polyclonal Antibody, HRP Conjugated
A70356	EpiGentek	Ask for price Ask for price Ask for price	100 ?g 50 ul 100 ul

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (Biotin)
20-abx336870	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 1 mg 200 ug 20 ug 50 ug

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (Biotin)
abx336870-100g	Abbexa	100 µg	EUR 362.5

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (Biotin)
abx336870-20g	Abbexa	20 µg	EUR 162.5

NUMB Like, Endocytic Adaptor Protein (NUMBL) Antibody (Biotin)
abx336870-50g	Abbexa	50 µg	EUR 250

NUMBL Polyclonal Antibody, FITC Conjugated
A70357	EpiGentek	Ask for price Ask for price Ask for price	100 ?g 50 ul 100 ul

NUMBL Polyclonal Antibody, Biotin Conjugated
A70358	EpiGentek	Ask for price Ask for price Ask for price	100 ?g 50 ul 100 ul

NUMBL
CSB-CL897595HU	Cusabio	10 μg plasmid + 200μl Glycerol	Ask for price

Numbl (GFP-tagged) - Mouse numb-like (Numbl)
MG209340	Origene Technologies GmbH	10 µg	Ask for price

Numbl (untagged) - Mouse numb-like (Numbl), (10ug)
MC202603	Origene Technologies GmbH	10 µg	Ask for price

Rabbit Anti Human NUMBL PolyClonal Antibody
MBS1491075-01mL	MyBiosource	0.1mL	EUR 335

Rabbit Anti Human NUMBL PolyClonal Antibody
MBS1491075-5x01mL	MyBiosource	5x0.1mL	EUR 1475

NUMBL mouse monoclonal antibody,clone OTI4A1
TA812189	Origene Technologies GmbH	100 µl	Ask for price

NUMBL mouse monoclonal antibody,clone OTI4A1
TA812189S	Origene Technologies GmbH	30 µl	Ask for price

NUMBL mouse monoclonal antibody,clone OTI6H7
TA812190	Origene Technologies GmbH	100 µl	Ask for price

NUMBL mouse monoclonal antibody,clone OTI6H7
TA812190S	Origene Technologies GmbH	30 µl	Ask for price

NUMBL mouse monoclonal antibody,clone OTI8D2
TA812202	Origene Technologies GmbH	100 µl	Ask for price

NUMBL mouse monoclonal antibody,clone OTI8D2
TA812202S	Origene Technologies GmbH	30 µl	Ask for price

Numbl (Myc-DDK-tagged) - Mouse numb-like (Numbl)
MR209340	Origene Technologies GmbH	10 µg	Ask for price

NUMBL, CT (NUMBL, Numb-like protein, Numb-related protein)
MBS649100-02mL	MyBiosource	0.2mL	EUR 695

NUMBL, CT (NUMBL, Numb-like protein, Numb-related protein)
MBS649100-5x02mL	MyBiosource	5x0.2mL	EUR 2975

NUMBL siRNA
20-abx926610	Abbexa	Ask for price Ask for price	15 nmol 30 nmol

NUMBL siRNA
20-abx926611	Abbexa	Ask for price Ask for price	15 nmol 30 nmol

NUMBL siRNA
20-abx903703	Abbexa	Ask for price Ask for price	15 nmol 30 nmol

NUMBL (untagged)-Human numb homolog (Drosophila)-like (NUMBL)
SC314186	Origene Technologies GmbH	10 µg	Ask for price

NUMBL Peptide
43-109P	ProSci	0.1 mg	EUR 405.6

NUMBL, CT (NUMBL, Numb-like protein, Numb-related protein) (AP)
MBS6327216-02mL	MyBiosource	0.2mL	EUR 980

NUMBL, CT (NUMBL, Numb-like protein, Numb-related protein) (AP)
MBS6327216-5x02mL	MyBiosource	5x0.2mL	EUR 4250

Five patients present ocular symptoms on onset. In eight asymptomatic patients remaining, the diagnosis of CMV retinitis is made by screening guided by a positive CMV infection. All patients can be evaluated responding to antivirus treatment but three shows an increase incomplete with the sequel to ocular. Our results show that the incidence of CMV retinitis after the Alogenic HSCT cannot be ignored and active ophthalmological screening is not only based on symptoms but also monitoring positive CMV infection contributes to early diagnosis of CMV retinitis.