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Human Cytomegalovirus Induces the Expression of the AMPKa2 Subunit to Drive Glycolytic Activation and Support Productive Viral Infection
The human cytomegalovirus infection (HCMV) modulates cellular metabolism to support viral replication. Kinase Kinase Kinase Calcium / Calmodulin (CAMKK) and Protein activated amp (AMPK) regulates metabolic activation and has been found important for successful HCMV infections. Here, we explore the specific contributions of camkk isoforms and ampk subunit isoforms to make HCMV infection. Our results show that various ISOFORM camkk and AMPK contribute to infection in a unique way.
For example, Camkk1 is important for HCMV infection in low infection multiplicity, but can be used for AMPK activation during the earliest infection, which is suggested by our data more dependent on camkk2. Our results also show that HCMV specifically induces the expression of catalytic subunit ampka2 non-ubiquitous, which is found important for glycolytic activation mediated by HCMV and high titers infections. Furthermore, we found that glycolytic activation mediated ampk was important for infection, as an excessive expression of glut4, high-capacity glucose transporter, some saved viral replication in the face of the inhibition of Ampk.
Collectively, our data shows that HCMV infection selectively induces specific metabolic regulation kinase expression, relying on their activities to support glycolytic activation and productive infection. The important virus is a mandatory parasite to provide energy and molecular building blocks to the masses to produce a descendant of the infectious virus. The process that regulates the modulation of cellular resource viruses has emerged as critical for successful infections.
Here, we find that HCMV depends on two kinase isoforms to support infection, camkk1 and ampka2. We found that HCMV specifically induces ampka2 subunit expression to induce metabolic activation and encourage strong viral replication. These results indicate that HCMV has evolved a mechanism to target certain metabolic regulatory kinase subunits to support productive infections, thus providing insight into how HCMV hijacked cellular metabolism for replication, and explained the vulnerability of potential virus therapy.
Cytomegalovirus cervical reactivation, cytokine, and spontaneous premature birth in Kenyan women
Activation of cytomegalovirus genital reactivation (CMV) is common during the third trimester of pregnancy. We hypothesize, cervical CMV shedding can increase the risk of spontaneous premature birth (SPTB) through the release of inflammatory cytokines in the cervix. We conducted a nesting case control analysis to determine the relationship between shedding CMV and SPTB using data and samples from prospective cohort studies in West Kenya. Women delivered between 28 + 0 and 33 + 6 weeks of pregnancy are adjusted to the gestational age on the collection of samples to control delivered ≥37 + 0 weeks.
The Level of CMV DNA and Interleukin (IL) -1 Beta (β), IL-6, IL-8, and Necrosis Factor-Alpha (TNF-α) tumors are measured in the servix. We use conditional logistic regression to assess the relationship between shedding cmv, cervical cytokine levels, and SPTB. Among the 86 cases and 86 suitable controls, cmv cervical levels are not significantly related to the SPTB (Odds Ratio [or] = 1.23, 95% trust interval [CI] 0.59-2.56), but significantly associated With higher IL-6 cervical levels. (β = 0.15, 95% CI 0.02-0.29) and TNF-α (β = 0.14, 95% CI 0.01-0.27). In univariate analysis, higher SPTB opportunities are associated with higher cervical IL-6 levels (or = 1.54, 95% CI 1.00-2.38), but not with other cervical cytokines. In this Kenyan women’s cohort, we did not find a significant relationship between cervical and SPTB shedding before 34 weeks.
Letermovir prophylaxis is effective in preventing reactivation of cytomegalovirus after alogenic hematopoietic cell transplantation: real single world data data
Morbidity and mortality after alogenic hematopoietic cell transplants (ALLOHCT) are still basically influenced by Cytomegalovirus (CMV) reactivation. We evaluate 80 seropositive patients transplanted in a row between March 2018 and March 2019 who received the prophylaxis of the Letermovir (leave) from engraftment to day +100 and retrospectively compare it with 80 patients without allowing allograft between January 2017 and March 2018.
The end point of research This is a cumulative incidence (CI) Clinically significant CMV infection (CS-CMVI) defined as CMV reactivation which demands preemptive treatment or CMV disease. With 14% CI CS-CMVI on the day +100 (11 events) significantly lower in let the cohort compared to the control group (33 events, 41%; HR 0.29; p <0.001). While therapy with Foscarnet can be fully avoided in the Group Leave, 7 out of 80 patients in the control cohort receiving Foscarnet, producing 151 extra patients for foscarnet (p = 0.002). The overall survival of one year is 72% on the control arm vs. 84% in the arms (HR 0.75 [95% CI 0.43-1.30]; P <0.306). This study confirms the efficacy and security let’s for the CS-CMVI prophylaxis after ALLOHCT in real-world settings, resulting in significant patient benefits by reducing hospitalization needs and exposure to antivirus drugs that are potentially toxic for the treatment of CMV reactivation.

Micrornas screening and validation and targets expressly expressed in hypertensive mice caused by cytomegalovirus infection
Introduction Some studies have suggested the relationship between Cytomegalovirus (CMV) infection and essential hypertension (eh). Micrornas (MIRNAS) plays an important role in developing EH by regulating specific target gene expression. However, a few are known about the role of MIRNA in uh induced by CMV. In this study, we compare the profile of Mirna’s expressions from samples from normal and murine cytomegalovirus (MCMV) -Infected C57BL / 6 mice using high-throughput sequencing analysis.
The method we collect thoracic aortic, heart tissue, and peripheral blood of twenty normal mice and twenty mice infected with MCMV. We identify Mirna which is expressly expressed in peripheral blood samples and predicts their target genes using bioinformatics tools. We then experimentally validated them using QRT-PCR and target genes with a double luciferase gene test test. The results we found 118 expressed by MIRNAs, including 9 MIRNAs was identified as potential hypertensive regulators induced by MCMV infection. We then validated the expression of two MIRAS candidates, MMU-MIR-1929-3P and MCMV-MIR-M01-4-5P, using QRT-PCR.
FBXO17 Blocking Peptide |
DF13006-BP |
Affbiotech |
1mg |
EUR 234 |
anti- FBXO18 antibody |
FNab03039 |
FN Test |
100µg |
EUR 658.5 |
|
Description: Antibody raised against FBXO18 |
anti- FBXO22 antibody |
FNab03041 |
FN Test |
100µg |
EUR 702 |
|
Description: Antibody raised against FBXO22 |
anti- FBXO28 antibody |
FNab03042 |
FN Test |
100µg |
EUR 702 |
|
Description: Antibody raised against FBXO28 |
anti- FBXO32 antibody |
FNab03044 |
FN Test |
100µg |
EUR 606.3 |
|
Description: Antibody raised against FBXO32 |
anti- FBXO41 antibody |
FNab03045 |
FN Test |
100µg |
EUR 658.5 |
|
Description: Antibody raised against FBXO41 |
anti- FBXO43 antibody |
FNab03046 |
FN Test |
100µg |
EUR 702 |
|
Description: Antibody raised against FBXO43 |
Rat FBXO17 shRNA Plasmid |
20-abx988576 |
Abbexa |
|
|
|
Mouse FBXO17 shRNA Plasmid |
20-abx974104 |
Abbexa |
|
|
|
Human FBXO17 shRNA Plasmid |
20-abx964438 |
Abbexa |
|
|
|
anti- FBXO2 antibody |
FNab03040 |
FN Test |
100µg |
EUR 606.3 |
|
Description: Antibody raised against FBXO2 |
anti- FBXO3 antibody |
FNab03043 |
FN Test |
100µg |
EUR 606.3 |
|
Description: Antibody raised against FBXO3 |
anti- FBXO5 antibody |
FNab03047 |
FN Test |
100µg |
EUR 658.5 |
|
Description: Antibody raised against FBXO5 |
anti- FBXO6 antibody |
FNab03048 |
FN Test |
100µg |
EUR 606.3 |
|
Description: Antibody raised against FBXO6 |
anti- FBXO7 antibody |
FNab03049 |
FN Test |
100µg |
EUR 702 |
|
Description: Antibody raised against FBXO7 |
anti- FBXO8 antibody |
FNab03050 |
FN Test |
100µg |
EUR 658.5 |
|
Description: Antibody raised against FBXO8 |
anti- FBXO9 antibody |
FNab03051 |
FN Test |
100µg |
EUR 658.5 |
|
Description: Antibody raised against FBXO9 |
FBXO17 Recombinant Protein (Rat) |
RP200984 |
ABM |
100 ug |
Ask for price |
FBXO17 Recombinant Protein (Human) |
RP011875 |
ABM |
100 ug |
Ask for price |
FBXO17 Recombinant Protein (Mouse) |
RP133955 |
ABM |
100 ug |
Ask for price |
Fbxo17 ORF Vector (Rat) (pORF) |
ORF066996 |
ABM |
1.0 ug DNA |
EUR 607.2 |
FBXO17 ORF Vector (Human) (pORF) |
ORF003959 |
ABM |
1.0 ug DNA |
EUR 114 |
Fbxo17 ORF Vector (Mouse) (pORF) |
ORF044653 |
ABM |
1.0 ug DNA |
EUR 607.2 |
Fbxo17 sgRNA CRISPR Lentivector set (Rat) |
K6558001 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
Fbxo17 sgRNA CRISPR Lentivector set (Mouse) |
K4857601 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
FBXO17 sgRNA CRISPR Lentivector set (Human) |
K0764701 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
Fbxo17 3'UTR GFP Stable Cell Line |
TU156413 |
ABM |
1.0 ml |
Ask for price |
FBXO17 3'UTR GFP Stable Cell Line |
TU057783 |
ABM |
1.0 ml |
EUR 2799.6 |
Fbxo17 3'UTR GFP Stable Cell Line |
TU254497 |
ABM |
1.0 ml |
Ask for price |
FBXO17 Protein Vector (Rat) (pPM-C-HA) |
PV267984 |
ABM |
500 ng |
EUR 723.6 |
FBXO17 Protein Vector (Rat) (pPB-C-His) |
PV267982 |
ABM |
500 ng |
EUR 723.6 |
FBXO17 Protein Vector (Rat) (pPB-N-His) |
PV267983 |
ABM |
500 ng |
EUR 723.6 |
FBXO17 Protein Vector (Rat) (pPM-C-His) |
PV267985 |
ABM |
500 ng |
EUR 723.6 |
FBXO17 Protein Vector (Human) (pPM-C-HA) |
PV015835 |
ABM |
500 ng |
EUR 394.8 |
FBXO17 Protein Vector (Mouse) (pPM-C-HA) |
PV178612 |
ABM |
500 ng |
EUR 723.6 |
FBXO17 Protein Vector (Human) (pPB-C-His) |
PV015833 |
ABM |
500 ng |
EUR 394.8 |
FBXO17 Protein Vector (Human) (pPB-N-His) |
PV015834 |
ABM |
500 ng |
EUR 394.8 |
FBXO17 Protein Vector (Human) (pPM-C-His) |
PV015836 |
ABM |
500 ng |
EUR 394.8 |
FBXO17 Protein Vector (Mouse) (pPB-C-His) |
PV178610 |
ABM |
500 ng |
EUR 723.6 |
FBXO17 Protein Vector (Mouse) (pPB-N-His) |
PV178611 |
ABM |
500 ng |
EUR 723.6 |
FBXO17 Protein Vector (Mouse) (pPM-C-His) |
PV178613 |
ABM |
500 ng |
EUR 723.6 |
FBXO17 3'UTR Luciferase Stable Cell Line |
TU007783 |
ABM |
1.0 ml |
EUR 2799.6 |
Fbxo17 3'UTR Luciferase Stable Cell Line |
TU106413 |
ABM |
1.0 ml |
Ask for price |
Fbxo17 3'UTR Luciferase Stable Cell Line |
TU204497 |
ABM |
1.0 ml |
Ask for price |
Fbxo17 sgRNA CRISPR Lentivector (Rat) (Target 1) |
K6558002 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Fbxo17 sgRNA CRISPR Lentivector (Rat) (Target 2) |
K6558003 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Fbxo17 sgRNA CRISPR Lentivector (Rat) (Target 3) |
K6558004 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Fbxo17 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
K4857602 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Fbxo17 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
K4857603 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Fbxo17 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
K4857604 |
ABM |
1.0 ug DNA |
EUR 184.8 |
FBXO17 sgRNA CRISPR Lentivector (Human) (Target 1) |
K0764702 |
ABM |
1.0 ug DNA |
EUR 184.8 |
FBXO17 sgRNA CRISPR Lentivector (Human) (Target 2) |
K0764703 |
ABM |
1.0 ug DNA |
EUR 184.8 |
FBXO17 sgRNA CRISPR Lentivector (Human) (Target 3) |
K0764704 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Human F-Box Protein 17 (FBXO17) ELISA Kit |
abx387316-96tests |
Abbexa |
96 tests |
EUR 1093.2 |
|
FBXO18 antibody |
10R-1565 |
Fitzgerald |
100 ug |
EUR 614.4 |
Description: Mouse monoclonal FBXO18 antibody |
FBXO21 antibody |
10R-4071 |
Fitzgerald |
100 ul |
EUR 829.2 |
Description: Mouse monoclonal FBXO21 antibody |
FBXO21 antibody |
10R-4072 |
Fitzgerald |
100 ul |
EUR 829.2 |
Description: Mouse monoclonal FBXO21 antibody |
FBXO21 antibody |
10R-4073 |
Fitzgerald |
100 ul |
EUR 871.2 |
Description: Mouse monoclonal FBXO21 antibody |
FBXO21 antibody |
10R-4074 |
Fitzgerald |
100 ul |
EUR 829.2 |
Description: Mouse monoclonal FBXO21 antibody |
FBXO21 antibody |
10R-4075 |
Fitzgerald |
100 ul |
EUR 829.2 |
Description: Mouse monoclonal FBXO21 antibody |
FBXO21 antibody |
10R-4077 |
Fitzgerald |
100 ul |
EUR 829.2 |
Description: Mouse monoclonal FBXO21 antibody |
FBXO21 antibody |
10R-4078 |
Fitzgerald |
100 ul |
EUR 829.2 |
Description: Mouse monoclonal FBXO21 antibody |
FBXO21 antibody |
10R-4079 |
Fitzgerald |
100 ul |
EUR 829.2 |
Description: Mouse monoclonal FBXO21 antibody |
FBXO31 antibody |
10R-6939 |
Fitzgerald |
100 ul |
EUR 871.2 |
Description: Mouse monoclonal FBXO31 antibody |
FBXO32 Antibody |
31096-100ul |
SAB |
100ul |
EUR 302.4 |
FBXO32 Antibody |
31096-50ul |
SAB |
50ul |
EUR 224.4 |
FBXO32 antibody |
38459-100ul |
SAB |
100ul |
EUR 302.4 |
FBXO11 antibody |
38737-100ul |
SAB |
100ul |
EUR 302.4 |
FBXO10 Antibody |
39860-100ul |
SAB |
100ul |
EUR 468 |
FBXO42 Antibody |
39863-100ul |
SAB |
100ul |
EUR 468 |
FBXO44 Antibody |
39864-100ul |
SAB |
100ul |
EUR 468 |
FBXO31 Antibody |
37567-100ul |
SAB |
100ul |
EUR 302.4 |
FBXO18 Antibody |
40045-100ul |
SAB |
100ul |
EUR 468 |
FBXO15 Antibody |
40046-100ul |
SAB |
100ul |
EUR 468 |
FBXO34 antibody |
43487-100ul |
SAB |
100ul |
EUR 302.4 |
FBXO34 antibody |
43487-50ul |
SAB |
50ul |
EUR 224.4 |
FBXO31 antibody |
70R-2500 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO31 antibody raised against the middle region of FBXO31 |
FBXO24 antibody |
70R-2787 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO24 antibody raised against the N terminal of FBXO24 |
FBXO25 antibody |
70R-2788 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO25 antibody raised against the N terminal of FBXO25 |
FBXO21 antibody |
70R-2799 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO21 antibody raised against the N terminal of FBXO21 |
FBXO11 antibody |
70R-2809 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO11 antibody raised against the middle region of FBXO11 |
FBXO24 antibody |
70R-2810 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO24 antibody raised against the middle region of FBXO24 |
FBXO24 antibody |
70R-2811 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO24 antibody raised against the middle region of FBXO24 |
FBXO32 antibody |
70R-9208 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Affinity purified rabbit polyclonal FBXO32 antibody |
Fbxo32 antibody |
70R-9209 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Affinity purified rabbit polyclonal Fbxo32 antibody |
FBXO31 antibody |
70R-9250 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Affinity purified rabbit polyclonal FBXO31 antibody |
Fbxo34 antibody |
70R-9473 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Affinity purified rabbit polyclonal Fbxo34 antibody |
FBXO25 antibody |
70R-1163 |
Fitzgerald |
100 ug |
EUR 452.4 |
Description: Rabbit polyclonal FBXO25 antibody raised against the C terminal of FBXO25 |
FBXO15 antibody |
70R-17256 |
Fitzgerald |
50 ul |
EUR 522 |
Description: Rabbit polyclonal FBXO15 antibody |
FBXO18 antibody |
70R-17257 |
Fitzgerald |
50 ul |
EUR 522 |
Description: Rabbit polyclonal FBXO18 antibody |
FBXO22 antibody |
70R-17259 |
Fitzgerald |
50 ul |
EUR 522 |
Description: Rabbit polyclonal FBXO22 antibody |
FBXO44 antibody |
70R-17261 |
Fitzgerald |
50 ul |
EUR 522 |
Description: Rabbit polyclonal FBXO44 antibody |
FBXO43 antibody |
70R-12858 |
Fitzgerald |
100 ul |
EUR 548.4 |
Description: Affinity purified Rabbit polyclonal FBXO43 antibody |
FBXO27 antibody |
70R-3150 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO27 antibody raised against the middle region of FBXO27 |
FBXO28 antibody |
70R-3153 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO28 antibody raised against the middle region of FBXO28 |
FBXO24 antibody |
70R-2248 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO24 antibody raised against the N terminal of FBXO24 |
FBXO24 antibody |
70R-2249 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO24 antibody raised against the middle region of FBXO24 |
FBXO10 antibody |
70R-3607 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO10 antibody raised against the middle region of FBXO10 |
FBXO22 antibody |
70R-3753 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO22 antibody raised against the middle region of FBXO22 |
FBXO16 antibody |
70R-3782 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO16 antibody raised against the N terminal of FBXO16 |
FBXO16 antibody |
70R-3783 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO16 antibody raised against the C terminal of FBXO16 |
FBXO36 antibody |
70R-3784 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO36 antibody raised against the N terminal of FBXO36 |
FBXO28 antibody |
70R-3792 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO28 antibody raised against the middle region of FBXO28 |
FBXO33 antibody |
70R-3799 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO33 antibody raised against the middle region of FBXO33 |
FBXO15 antibody |
70R-4393 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO15 antibody raised against the N terminal of FBXO15 |
FBXO39 antibody |
70R-3430 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO39 antibody raised against the N terminal of FBXO39 |
FBXO39 antibody |
70R-3431 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO39 antibody raised against the middle region of FBXO39 |
FBXO34 antibody |
70R-3482 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO34 antibody raised against the middle region of FBXO34 |
FBXO42 antibody |
70R-3602 |
Fitzgerald |
50 ug |
EUR 560.4 |
Description: Rabbit polyclonal FBXO42 antibody raised against the middle region of FBXO42 |
FBXO45 antibody |
31960-100ul |
SAB |
100ul |
EUR 302.4 |
FBXO45 antibody |
31960-50ul |
SAB |
50ul |
EUR 224.4 |
FBXO16 Antibody |
47548-100ul |
SAB |
100ul |
EUR 302.4 |
FBXO32 Antibody |
1-CSB-PA996906 |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO32. Recognizes FBXO32 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 |
FBXO31 Antibody |
1-CSB-PA093129 |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO31. Recognizes FBXO31 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200 |
FBXO10 Antibody |
1-CSB-PA890915LA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO10. Recognizes FBXO10 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200 |
FBXO31 Antibody |
1-CSB-PA907885 |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO31. Recognizes FBXO31 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200 |
FBXO44 Antibody |
1-CSB-PA872497LA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO44. Recognizes FBXO44 from Human. This antibody is Unconjugated. Tested in the following application: ELISA |
FBXO15 Antibody |
1-CSB-PA843324LA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO15. Recognizes FBXO15 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
FBXO30 Antibody |
1-CSB-PA844709LA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO30. Recognizes FBXO30 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
FBXO25 Antibody |
1-CSB-PA848401LA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO25. Recognizes FBXO25 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
FBXO22 Antibody |
1-CSB-PA854115ESR1HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO22. Recognizes FBXO22 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
FBXO22 Antibody |
1-CSB-PA854115ESR2HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO22. Recognizes FBXO22 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
FBXO40 Antibody |
1-CSB-PA883385LA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO40. Recognizes FBXO40 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
FBXO28 Antibody |
1-CSB-PA889119LA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO28. Recognizes FBXO28 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
FBXO44 Antibody |
1-CSB-PA008509GA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO44. Recognizes FBXO44 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA |
FBXO15 Antibody |
1-CSB-PA008483GA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO15. Recognizes FBXO15 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB |
FBXO18 Antibody |
1-CSB-PA008486GA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO18. Recognizes FBXO18 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB |
FBXO22 Antibody |
1-CSB-PA008489GA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO22. Recognizes FBXO22 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC |
FBXO24 Antibody |
1-CSB-PA008491LA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against FBXO24. Recognizes FBXO24 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:1000-1:5000 |
FBXO32 Antibody |
R34914-100UG |
NSJ Bioreagents |
100 ug |
EUR 339.15 |
Description: Additional name(s) for this target protein: F-box protein 32 |
FBXO43 Antibody |
R35015-100UG |
NSJ Bioreagents |
100 ug |
EUR 339.15 |
Description: Additional name(s) for this target protein: F-box protein 43, early mitotic inhibitor 2, EMI2 |
FBXO44 Antibody |
R33107-100UG |
NSJ Bioreagents |
100 ug |
EUR 339.15 |
Description: Additional name(s) for this target protein: F-box protein 44 |
Rat F box only protein 17(FBXO17) ELISA kit |
E02F0279-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat F box only protein 17(FBXO17) ELISA kit |
E02F0279-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat F box only protein 17(FBXO17) ELISA kit |
E02F0279-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig F box only protein 17(FBXO17) ELISA kit |
E07F0279-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Porcine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig F box only protein 17(FBXO17) ELISA kit |
E07F0279-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Porcine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig F box only protein 17(FBXO17) ELISA kit |
E07F0279-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Porcine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog F box only protein 17(FBXO17) ELISA kit |
E08F0279-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Canine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog F box only protein 17(FBXO17) ELISA kit |
E08F0279-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Canine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog F box only protein 17(FBXO17) ELISA kit |
E08F0279-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Canine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat F box only protein 17(FBXO17) ELISA kit |
E06F0279-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Goat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat F box only protein 17(FBXO17) ELISA kit |
E06F0279-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Goat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat F box only protein 17(FBXO17) ELISA kit |
E06F0279-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Goat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
FBXO17 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV) |
LV665293 |
ABM |
1.0 ug DNA |
EUR 616.8 |
FBXO17 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC) |
LV665297 |
ABM |
1.0 ug DNA |
EUR 616.8 |
FBXO40 Antibody (HRP) |
20-abx311700 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
FBXO44 Antibody (HRP) |
20-abx311174 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
FBXO15 Antibody (HRP) |
20-abx309699 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Mouse F box only protein 17(FBXO17) ELISA kit |
E03F0279-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Mouse F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse F box only protein 17(FBXO17) ELISA kit |
E03F0279-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Mouse F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Furthermore, the dual-luciferase reporter gene test revealed that the area 3′-untranslated (UTR) endothelin A receptor (Ednra) MRNA contains a binding site for MMU-MIR-1929-3P. Collectively, our data shows that MCMV infection can increase blood pressure and reduce MMU-MIR-1929-3P expression in C57BL / 6. In addition, we find that MMU-MIR-1929-3P targets 3 ‘UTR from MRNA Ednra. Conclusion This new regulation axis can help develop a new approach to clinical prevention and control eh.