Human Cytomegalovirus Induces the Expression of the AMPKa2 Subunit to Drive Glycolytic Activation and Support Productive Viral Infection

Human Cytomegalovirus Induces the Expression of the AMPKa2 Subunit to Drive Glycolytic Activation and Support Productive Viral Infection

The human cytomegalovirus infection (HCMV) modulates cellular metabolism to support viral replication. Kinase Kinase Kinase Calcium / Calmodulin (CAMKK) and Protein activated amp (AMPK) regulates metabolic activation and has been found important for successful HCMV infections. Here, we explore the specific contributions of camkk isoforms and ampk subunit isoforms to make HCMV infection. Our results show that various ISOFORM camkk and AMPK contribute to infection in a unique way.

For example, Camkk1 is important for HCMV infection in low infection multiplicity, but can be used for AMPK activation during the earliest infection, which is suggested by our data more dependent on camkk2. Our results also show that HCMV specifically induces the expression of catalytic subunit ampka2 non-ubiquitous, which is found important for glycolytic activation mediated by HCMV and high titers infections. Furthermore, we found that glycolytic activation mediated ampk was important for infection, as an excessive expression of glut4, high-capacity glucose transporter, some saved viral replication in the face of the inhibition of Ampk.

Collectively, our data shows that HCMV infection selectively induces specific metabolic regulation kinase expression, relying on their activities to support glycolytic activation and productive infection. The important virus is a mandatory parasite to provide energy and molecular building blocks to the masses to produce a descendant of the infectious virus. The process that regulates the modulation of cellular resource viruses has emerged as critical for successful infections.

Here, we find that HCMV depends on two kinase isoforms to support infection, camkk1 and ampka2. We found that HCMV specifically induces ampka2 subunit expression to induce metabolic activation and encourage strong viral replication. These results indicate that HCMV has evolved a mechanism to target certain metabolic regulatory kinase subunits to support productive infections, thus providing insight into how HCMV hijacked cellular metabolism for replication, and explained the vulnerability of potential virus therapy.

Cytomegalovirus cervical reactivation, cytokine, and spontaneous premature birth in Kenyan women

Activation of cytomegalovirus genital reactivation (CMV) is common during the third trimester of pregnancy. We hypothesize, cervical CMV shedding can increase the risk of spontaneous premature birth (SPTB) through the release of inflammatory cytokines in the cervix. We conducted a nesting case control analysis to determine the relationship between shedding CMV and SPTB using data and samples from prospective cohort studies in West Kenya. Women delivered between 28 + 0 and 33 + 6 weeks of pregnancy are adjusted to the gestational age on the collection of samples to control delivered ≥37 + 0 weeks.

The Level of CMV DNA and Interleukin (IL) -1 Beta (β), IL-6, IL-8, and Necrosis Factor-Alpha (TNF-α) tumors are measured in the servix. We use conditional logistic regression to assess the relationship between shedding cmv, cervical cytokine levels, and SPTB. Among the 86 cases and 86 suitable controls, cmv cervical levels are not significantly related to the SPTB (Odds Ratio [or] = 1.23, 95% trust interval [CI] 0.59-2.56), but significantly associated With higher IL-6 cervical levels. (β = 0.15, 95% CI 0.02-0.29) and TNF-α (β = 0.14, 95% CI 0.01-0.27). In univariate analysis, higher SPTB opportunities are associated with higher cervical IL-6 levels (or = 1.54, 95% CI 1.00-2.38), but not with other cervical cytokines. In this Kenyan women’s cohort, we did not find a significant relationship between cervical and SPTB shedding before 34 weeks.

Letermovir prophylaxis is effective in preventing reactivation of cytomegalovirus after alogenic hematopoietic cell transplantation: real single world data data

Morbidity and mortality after alogenic hematopoietic cell transplants (ALLOHCT) are still basically influenced by Cytomegalovirus (CMV) reactivation. We evaluate 80 seropositive patients transplanted in a row between March 2018 and March 2019 who received the prophylaxis of the Letermovir (leave) from engraftment to day +100 and retrospectively compare it with 80 patients without allowing allograft between January 2017 and March 2018.

The end point of research This is a cumulative incidence (CI) Clinically significant CMV infection (CS-CMVI) defined as CMV reactivation which demands preemptive treatment or CMV disease. With 14% CI CS-CMVI on the day +100 (11 events) significantly lower in let the cohort compared to the control group (33 events, 41%; HR 0.29; p <0.001). While therapy with Foscarnet can be fully avoided in the Group Leave, 7 out of 80 patients in the control cohort receiving Foscarnet, producing 151 extra patients for foscarnet (p = 0.002). The overall survival of one year is 72% on the control arm vs. 84% in the arms (HR 0.75 [95% CI 0.43-1.30]; P <0.306). This study confirms the efficacy and security let’s for the CS-CMVI prophylaxis after ALLOHCT in real-world settings, resulting in significant patient benefits by reducing hospitalization needs and exposure to antivirus drugs that are potentially toxic for the treatment of CMV reactivation.

Human Cytomegalovirus Induces the Expression of the AMPKa2 Subunit to Drive Glycolytic Activation and Support Productive Viral Infection

Micrornas screening and validation and targets expressly expressed in hypertensive mice caused by cytomegalovirus infection

Introduction Some studies have suggested the relationship between Cytomegalovirus (CMV) infection and essential hypertension (eh). Micrornas (MIRNAS) plays an important role in developing EH by regulating specific target gene expression. However, a few are known about the role of MIRNA in uh induced by CMV. In this study, we compare the profile of Mirna’s expressions from samples from normal and murine cytomegalovirus (MCMV) -Infected C57BL / 6 mice using high-throughput sequencing analysis.

The method we collect thoracic aortic, heart tissue, and peripheral blood of twenty normal mice and twenty mice infected with MCMV. We identify Mirna which is expressly expressed in peripheral blood samples and predicts their target genes using bioinformatics tools. We then experimentally validated them using QRT-PCR and target genes with a double luciferase gene test test. The results we found 118 expressed by MIRNAs, including 9 MIRNAs was identified as potential hypertensive regulators induced by MCMV infection. We then validated the expression of two MIRAS candidates, MMU-MIR-1929-3P and MCMV-MIR-M01-4-5P, using QRT-PCR.

FBXO17 Blocking Peptide

DF13006-BP 1mg
EUR 234

FBXO17 cloning plasmid

CSB-CL853409HU-10ug 10ug
EUR 411.6
Description: A cloning plasmid for the FBXO17 gene.

pCMV-SPORT6-FBXO17

PVT13625 2 ug
EUR 469.2

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form

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Polyclonal Goat anti-GST p-form

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Human FBXO17 shRNA Plasmid

20-abx964438
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse FBXO17 shRNA Plasmid

20-abx974104
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  • 150 µg
  • 300 µg

Rat FBXO17 shRNA Plasmid

20-abx988576
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

FBXO17 ELISA KIT|Human

EF009580 96 Tests
EUR 826.8

FBXO17 Recombinant Protein (Human)

RP011875 100 ug Ask for price

FBXO17 Recombinant Protein (Rat)

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FBXO17 Recombinant Protein (Mouse)

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F-Box Protein 17 (FBXO17) Antibody

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EUR 577.2

Fbxo17 ORF Vector (Rat) (pORF)

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Fbxo17 ORF Vector (Mouse) (pORF)

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FBXO17 sgRNA CRISPR Lentivector set (Human)

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Fbxo17 sgRNA CRISPR Lentivector set (Mouse)

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Fbxo17 sgRNA CRISPR Lentivector set (Rat)

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FBXO17 sgRNA CRISPR Lentivector (Human) (Target 1)

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FBXO17 Protein Vector (Rat) (pPB-C-His)

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Human F-Box Protein 17 (FBXO17) ELISA Kit

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FBXO17 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

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Goat F box only protein 17(FBXO17) ELISA kit

E06F0279-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat F box only protein 17(FBXO17) ELISA kit

E06F0279-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat F box only protein 17(FBXO17) ELISA kit

E06F0279-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit F box only protein 17(FBXO17) ELISA kit

E04F0279-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit F box only protein 17(FBXO17) ELISA kit

E04F0279-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit F box only protein 17(FBXO17) ELISA kit

E04F0279-96 1 plate of 96 wells
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Description: A competitive ELISA for quantitative measurement of Rabbit F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse F box only protein 17(FBXO17) ELISA kit

E03F0279-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse F box only protein 17(FBXO17) ELISA kit

E03F0279-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse F box only protein 17(FBXO17) ELISA kit

E03F0279-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig F box only protein 17(FBXO17) ELISA kit

E07F0279-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig F box only protein 17(FBXO17) ELISA kit

E07F0279-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig F box only protein 17(FBXO17) ELISA kit

E07F0279-96 1 plate of 96 wells
EUR 822
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Dog F box only protein 17(FBXO17) ELISA kit

E08F0279-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog F box only protein 17(FBXO17) ELISA kit

E08F0279-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog F box only protein 17(FBXO17) ELISA kit

E08F0279-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey F box only protein 17(FBXO17) ELISA kit

E09F0279-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey F box only protein 17(FBXO17) ELISA kit

E09F0279-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey F box only protein 17(FBXO17) ELISA kit

E09F0279-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat F box only protein 17(FBXO17) ELISA kit

E02F0279-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat F box only protein 17(FBXO17) ELISA kit

E02F0279-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat F box only protein 17(FBXO17) ELISA kit

E02F0279-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human F- box only protein 17, FBXO17 ELISA KIT

ELI-48580h 96 Tests
EUR 988.8

Human F box only protein 17(FBXO17) ELISA kit

E01F0279-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human F box only protein 17(FBXO17) ELISA kit

E01F0279-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human F box only protein 17(FBXO17) ELISA kit

E01F0279-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse F- box only protein 17, Fbxo17 ELISA KIT

ELI-12874m 96 Tests
EUR 1038

Guinea pig F box only protein 17(FBXO17) ELISA kit

E05F0279-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig F box only protein 17(FBXO17) ELISA kit

E05F0279-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig F box only protein 17(FBXO17) ELISA kit

E05F0279-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

FBXO17 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0764705 3 x 1.0 ug
EUR 451.2

Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4857605 3 x 1.0 ug
EUR 451.2

Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

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EUR 451.2

FBXO17 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

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EUR 616.8

FBXO17 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV665295 1.0 ug DNA
EUR 686.4

FBXO17 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

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FBXO17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

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EUR 200.4

FBXO17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

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FBXO17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

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Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

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Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

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Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

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Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

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Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 332.4
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 332.4

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 332.4
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 332.4

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 332.4

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 332.4

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 332.4

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-DDB1 Antibody

A00333 100uL
EUR 546
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-10x96wellstestplate 10x96-wells test plate
EUR 6777.36
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x48wellstestplate 1x48-wells test plate
EUR 663.31
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x96wellstestplate 1x96-wells test plate
EUR 896.16
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-5x96wellstestplate 5x96-wells test plate
EUR 3672.72
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

4-AEA465Hu
  • EUR 6837.60
  • EUR 3613.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody)

ELK8071 1 plate of 96 wells
EUR 518.4
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti-ZNF660 antibody

44742-100ul 100ul
EUR 302.4

Anti-ZNF660 antibody

44742-50ul 50ul
EUR 224.4

Anti-CCV Antibody

10-2789 1 mg
EUR 217.2
Description: Anti-Canine Corona Virus Antibody

Anti-CCV Antibody

10-2790 1 mg
EUR 217.2
Description: Anti-Canine Corona Virus Antibody

Anti-CDV antibody

10-2791 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CDV antibody

10-2792 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CDV antibody

10-2793 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CDV antibody

10-2794 1 mg
EUR 198
Description: Anti-Canine Distemper Virus antibody

Anti-CPV Antibody

10-2795 500 uig
EUR 165.6
Description: Anti-Canine Parvo Virus Antibody

Anti-CPV Antibody

10-2796 500 ug
EUR 165.6
Description: Anti-Canine Parvo Virus Antibody

Anti-CPV Antibody

10-2797 500 ug
EUR 165.6
Description: Anti-Canine Parvo Virus Antibody

Anti-C.CRP antibody

10-2798 500 ug
EUR 165.6
Description: Anti-Canine CRP antibody

Anti-C.CRP antibody

10-2799 500 ug
EUR 165.6
Description: Anti-Canine CRP antibody

Anti-CHW antibody

10-2800 1 mg
EUR 198
Description: Anti-Canine Heartworm antibody

Anti-FeLV antibody

10-2801 1 mg
EUR 217.2
Description: Anti-Feline Leukemia Virus antibody

Anti-FeLV antibody

10-2802 1 mg
EUR 217.2
Description: Anti-Feline Leukemia Virus antibody

Anti-FeLV antibody

10-2803 1 mg
EUR 217.2
Description: Anti-Feline Leukemia Virus antibody

Anti-PGI antibody

10-2806 1 mg
EUR 502.8
Description: Anti-PGI recombinant antibody

Anti-PGI antibody

10-2807 1 mg
EUR 502.8
Description: Anti-PGI recombinant antibody

Anti-PGII antibody

10-2808 1 mg
EUR 502.8
Description: Anti-PGII recombinant antibody

Anti-PGII antibody

10-2809 1 mg
EUR 502.8
Description: Anti-PGII recombinant antibody

Anti-CHW antibody

10-2810 1 mg
EUR 198
Description: Anti-CHW monoclonal antibody

Anti-Giardia antibody

10-2811 1 mg
EUR 198
Description: Anti-Giardia monoclonal antibody

Anti-Giardia antibody

10-2812 1 mg
EUR 198
Description: Anti-Giardia monoclonal antibody

Anti-TAP1 Antibody

A01123 100ul
EUR 476.4
Description: Rabbit Polyclonal TAP1 Antibody. Validated in IP, IHC, WB and tested in Human, Rat.

Anti-CHD4 Antibody

A01125 100ul
EUR 476.4
Description: Rabbit Polyclonal CHD4 Antibody. Validated in IF, IHC and tested in Human, Mouse.

Anti-NRF1 Antibody

A01129-2 100ug/vial
EUR 400.8

Anti-MEF2C Antibody

A01131-1 100ug/vial
EUR 400.8

Anti-SCN4A Antibody

A01138 100ul
EUR 476.4
Description: Rabbit Polyclonal SCN4A Antibody. Validated in WB and tested in Human.

Anti-MTR Antibody

A01140-2 100ug/vial
EUR 400.8

Anti-IL12B Antibody

A01152-2 100ug/vial
EUR 352.8

Anti-IL12B Antibody

A01152-3 100ug/vial
EUR 400.8

Anti-IL12B Antibody

A01152-4 100ug/vial
EUR 352.8

Anti-IL11 Antibody

A01160-1 100ug/vial
EUR 352.8

Anti-Bak Antibody

A01163 200ug
EUR 626.4
Description: Rabbit Polyclonal Bak Antibody. Validated in IP, IF, IHC, WB and tested in Human.

Anti-PGF Antibody

A01164-1 100ug/vial
EUR 352.8

Anti-PGF Antibody

A01164-2 100ug/vial
EUR 352.8

Anti-CD201 Antibody

A01166 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for CD201 Antibody (PROCR) detection.tested for IHC, WB in Human, Mouse, Rat.

Anti-SERCA2 Antibody

A01176 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for SERCA2 Antibody (ATP2A2) detection.tested for IHC, WB in Human, Mouse, Rat.

Anti-XPA Antibody

A01182 100ul
EUR 476.4
Description: Rabbit Polyclonal XPA Antibody. Validated in IHC, WB and tested in Human.

Anti-XPA Antibody

A01182-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for XPA Antibody (XPA) detection.tested for WB in Human, Mouse.

Anti-XPA Antibody

A01182-2 100ug/vial
EUR 352.8

Furthermore, the dual-luciferase reporter gene test revealed that the area 3′-untranslated (UTR) endothelin A receptor (Ednra) MRNA contains a binding site for MMU-MIR-1929-3P. Collectively, our data shows that MCMV infection can increase blood pressure and reduce MMU-MIR-1929-3P expression in C57BL / 6. In addition, we find that MMU-MIR-1929-3P targets 3 ‘UTR from MRNA Ednra. Conclusion This new regulation axis can help develop a new approach to clinical prevention and control eh.

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