Human Cytomegalovirus Induces the Expression of the AMPKa2 Subunit to Drive Glycolytic Activation and Support Productive Viral Infection

Human Cytomegalovirus Induces the Expression of the AMPKa2 Subunit to Drive Glycolytic Activation and Support Productive Viral Infection

The human cytomegalovirus infection (HCMV) modulates cellular metabolism to support viral replication. Kinase Kinase Kinase Calcium / Calmodulin (CAMKK) and Protein activated amp (AMPK) regulates metabolic activation and has been found important for successful HCMV infections. Here, we explore the specific contributions of camkk isoforms and ampk subunit isoforms to make HCMV infection. Our results show that various ISOFORM camkk and AMPK contribute to infection in a unique way.

For example, Camkk1 is important for HCMV infection in low infection multiplicity, but can be used for AMPK activation during the earliest infection, which is suggested by our data more dependent on camkk2. Our results also show that HCMV specifically induces the expression of catalytic subunit ampka2 non-ubiquitous, which is found important for glycolytic activation mediated by HCMV and high titers infections. Furthermore, we found that glycolytic activation mediated ampk was important for infection, as an excessive expression of glut4, high-capacity glucose transporter, some saved viral replication in the face of the inhibition of Ampk.

Collectively, our data shows that HCMV infection selectively induces specific metabolic regulation kinase expression, relying on their activities to support glycolytic activation and productive infection. The important virus is a mandatory parasite to provide energy and molecular building blocks to the masses to produce a descendant of the infectious virus. The process that regulates the modulation of cellular resource viruses has emerged as critical for successful infections.

Here, we find that HCMV depends on two kinase isoforms to support infection, camkk1 and ampka2. We found that HCMV specifically induces ampka2 subunit expression to induce metabolic activation and encourage strong viral replication. These results indicate that HCMV has evolved a mechanism to target certain metabolic regulatory kinase subunits to support productive infections, thus providing insight into how HCMV hijacked cellular metabolism for replication, and explained the vulnerability of potential virus therapy.

Cytomegalovirus cervical reactivation, cytokine, and spontaneous premature birth in Kenyan women

Activation of cytomegalovirus genital reactivation (CMV) is common during the third trimester of pregnancy. We hypothesize, cervical CMV shedding can increase the risk of spontaneous premature birth (SPTB) through the release of inflammatory cytokines in the cervix. We conducted a nesting case control analysis to determine the relationship between shedding CMV and SPTB using data and samples from prospective cohort studies in West Kenya. Women delivered between 28 + 0 and 33 + 6 weeks of pregnancy are adjusted to the gestational age on the collection of samples to control delivered ≥37 + 0 weeks.

The Level of CMV DNA and Interleukin (IL) -1 Beta (β), IL-6, IL-8, and Necrosis Factor-Alpha (TNF-α) tumors are measured in the servix. We use conditional logistic regression to assess the relationship between shedding cmv, cervical cytokine levels, and SPTB. Among the 86 cases and 86 suitable controls, cmv cervical levels are not significantly related to the SPTB (Odds Ratio [or] = 1.23, 95% trust interval [CI] 0.59-2.56), but significantly associated With higher IL-6 cervical levels. (β = 0.15, 95% CI 0.02-0.29) and TNF-α (β = 0.14, 95% CI 0.01-0.27). In univariate analysis, higher SPTB opportunities are associated with higher cervical IL-6 levels (or = 1.54, 95% CI 1.00-2.38), but not with other cervical cytokines. In this Kenyan women’s cohort, we did not find a significant relationship between cervical and SPTB shedding before 34 weeks.

Letermovir prophylaxis is effective in preventing reactivation of cytomegalovirus after alogenic hematopoietic cell transplantation: real single world data data

Morbidity and mortality after alogenic hematopoietic cell transplants (ALLOHCT) are still basically influenced by Cytomegalovirus (CMV) reactivation. We evaluate 80 seropositive patients transplanted in a row between March 2018 and March 2019 who received the prophylaxis of the Letermovir (leave) from engraftment to day +100 and retrospectively compare it with 80 patients without allowing allograft between January 2017 and March 2018.

The end point of research This is a cumulative incidence (CI) Clinically significant CMV infection (CS-CMVI) defined as CMV reactivation which demands preemptive treatment or CMV disease. With 14% CI CS-CMVI on the day +100 (11 events) significantly lower in let the cohort compared to the control group (33 events, 41%; HR 0.29; p <0.001). While therapy with Foscarnet can be fully avoided in the Group Leave, 7 out of 80 patients in the control cohort receiving Foscarnet, producing 151 extra patients for foscarnet (p = 0.002). The overall survival of one year is 72% on the control arm vs. 84% in the arms (HR 0.75 [95% CI 0.43-1.30]; P <0.306). This study confirms the efficacy and security let’s for the CS-CMVI prophylaxis after ALLOHCT in real-world settings, resulting in significant patient benefits by reducing hospitalization needs and exposure to antivirus drugs that are potentially toxic for the treatment of CMV reactivation.

Human Cytomegalovirus Induces the Expression of the AMPKa2 Subunit to Drive Glycolytic Activation and Support Productive Viral Infection

Micrornas screening and validation and targets expressly expressed in hypertensive mice caused by cytomegalovirus infection

Introduction Some studies have suggested the relationship between Cytomegalovirus (CMV) infection and essential hypertension (eh). Micrornas (MIRNAS) plays an important role in developing EH by regulating specific target gene expression. However, a few are known about the role of MIRNA in uh induced by CMV. In this study, we compare the profile of Mirna’s expressions from samples from normal and murine cytomegalovirus (MCMV) -Infected C57BL / 6 mice using high-throughput sequencing analysis.

The method we collect thoracic aortic, heart tissue, and peripheral blood of twenty normal mice and twenty mice infected with MCMV. We identify Mirna which is expressly expressed in peripheral blood samples and predicts their target genes using bioinformatics tools. We then experimentally validated them using QRT-PCR and target genes with a double luciferase gene test test. The results we found 118 expressed by MIRNAs, including 9 MIRNAs was identified as potential hypertensive regulators induced by MCMV infection. We then validated the expression of two MIRAS candidates, MMU-MIR-1929-3P and MCMV-MIR-M01-4-5P, using QRT-PCR.

FBXO17 Blocking Peptide

DF13006-BP 1mg
EUR 195

pCMV-SPORT6-FBXO17

PVT13625 2 ug
EUR 391

FBXO17 cloning plasmid

CSB-CL853409HU-10ug 10ug
EUR 343
Description: A cloning plasmid for the FBXO17 gene.

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

FBXO17 ELISA KIT|Human

EF009580 96 Tests
EUR 689

FBXO17 Recombinant Protein (Human)

RP011875 100 ug Ask for price

FBXO17 Recombinant Protein (Rat)

RP200984 100 ug Ask for price

FBXO17 Recombinant Protein (Mouse)

RP133955 100 ug Ask for price

Mouse FBXO17 shRNA Plasmid

20-abx974104
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Rat FBXO17 shRNA Plasmid

20-abx988576
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Human FBXO17 shRNA Plasmid

20-abx964438
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

F-Box Protein 17 (FBXO17) Antibody

abx233038-100ug 100 ug
EUR 481

Fbxo17 ORF Vector (Rat) (pORF)

ORF066996 1.0 ug DNA
EUR 506

FBXO17 ORF Vector (Human) (pORF)

ORF003959 1.0 ug DNA
EUR 95

Fbxo17 ORF Vector (Mouse) (pORF)

ORF044653 1.0 ug DNA
EUR 506

Fbxo17 sgRNA CRISPR Lentivector set (Mouse)

K4857601 3 x 1.0 ug
EUR 339

Fbxo17 sgRNA CRISPR Lentivector set (Rat)

K6558001 3 x 1.0 ug
EUR 339

FBXO17 sgRNA CRISPR Lentivector set (Human)

K0764701 3 x 1.0 ug
EUR 339

FBXO17 3'UTR Luciferase Stable Cell Line

TU007783 1.0 ml
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Fbxo17 3'UTR GFP Stable Cell Line

TU156413 1.0 ml Ask for price

Fbxo17 3'UTR Luciferase Stable Cell Line

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Fbxo17 3'UTR Luciferase Stable Cell Line

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Fbxo17 3'UTR GFP Stable Cell Line

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FBXO17 3'UTR GFP Stable Cell Line

TU057783 1.0 ml
EUR 2333

FBXO17 Protein Vector (Mouse) (pPB-C-His)

PV178610 500 ng
EUR 603

FBXO17 Protein Vector (Mouse) (pPB-N-His)

PV178611 500 ng
EUR 603

FBXO17 Protein Vector (Mouse) (pPM-C-HA)

PV178612 500 ng
EUR 603

FBXO17 Protein Vector (Mouse) (pPM-C-His)

PV178613 500 ng
EUR 603

FBXO17 Protein Vector (Rat) (pPB-C-His)

PV267982 500 ng
EUR 603

FBXO17 Protein Vector (Rat) (pPB-N-His)

PV267983 500 ng
EUR 603

FBXO17 Protein Vector (Rat) (pPM-C-HA)

PV267984 500 ng
EUR 603

FBXO17 Protein Vector (Rat) (pPM-C-His)

PV267985 500 ng
EUR 603

Fbxo17 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4857602 1.0 ug DNA
EUR 154

Fbxo17 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4857603 1.0 ug DNA
EUR 154

Fbxo17 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4857604 1.0 ug DNA
EUR 154

Fbxo17 sgRNA CRISPR Lentivector (Rat) (Target 1)

K6558002 1.0 ug DNA
EUR 154

Fbxo17 sgRNA CRISPR Lentivector (Rat) (Target 2)

K6558003 1.0 ug DNA
EUR 154

Fbxo17 sgRNA CRISPR Lentivector (Rat) (Target 3)

K6558004 1.0 ug DNA
EUR 154

FBXO17 Protein Vector (Human) (pPB-C-His)

PV015833 500 ng
EUR 329

FBXO17 Protein Vector (Human) (pPB-N-His)

PV015834 500 ng
EUR 329

FBXO17 Protein Vector (Human) (pPM-C-HA)

PV015835 500 ng
EUR 329

FBXO17 Protein Vector (Human) (pPM-C-His)

PV015836 500 ng
EUR 329

FBXO17 sgRNA CRISPR Lentivector (Human) (Target 1)

K0764702 1.0 ug DNA
EUR 154

FBXO17 sgRNA CRISPR Lentivector (Human) (Target 2)

K0764703 1.0 ug DNA
EUR 154

FBXO17 sgRNA CRISPR Lentivector (Human) (Target 3)

K0764704 1.0 ug DNA
EUR 154

FBXO17 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV665293 1.0 ug DNA
EUR 514

FBXO17 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV665297 1.0 ug DNA
EUR 514

FBXO17 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV665298 1.0 ug DNA
EUR 514

Human F-Box Protein 17 (FBXO17) ELISA Kit

abx387316-96tests 96 tests
EUR 911

Mouse F- box only protein 17, Fbxo17 ELISA KIT

ELI-12874m 96 Tests
EUR 865

Human F box only protein 17(FBXO17) ELISA kit

E01F0279-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human F box only protein 17(FBXO17) ELISA kit

E01F0279-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human F box only protein 17(FBXO17) ELISA kit

E01F0279-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse F box only protein 17(FBXO17) ELISA kit

E03F0279-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse F box only protein 17(FBXO17) ELISA kit

E03F0279-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse F box only protein 17(FBXO17) ELISA kit

E03F0279-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat F box only protein 17(FBXO17) ELISA kit

E02F0279-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat F box only protein 17(FBXO17) ELISA kit

E02F0279-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat F box only protein 17(FBXO17) ELISA kit

E02F0279-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey F box only protein 17(FBXO17) ELISA kit

E09F0279-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey F box only protein 17(FBXO17) ELISA kit

E09F0279-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey F box only protein 17(FBXO17) ELISA kit

E09F0279-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog F box only protein 17(FBXO17) ELISA kit

E08F0279-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog F box only protein 17(FBXO17) ELISA kit

E08F0279-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Canine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog F box only protein 17(FBXO17) ELISA kit

E08F0279-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Canine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig F box only protein 17(FBXO17) ELISA kit

E07F0279-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig F box only protein 17(FBXO17) ELISA kit

E07F0279-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig F box only protein 17(FBXO17) ELISA kit

E07F0279-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit F box only protein 17(FBXO17) ELISA kit

E04F0279-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit F box only protein 17(FBXO17) ELISA kit

E04F0279-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit F box only protein 17(FBXO17) ELISA kit

E04F0279-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat F box only protein 17(FBXO17) ELISA kit

E06F0279-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat F box only protein 17(FBXO17) ELISA kit

E06F0279-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Goat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat F box only protein 17(FBXO17) ELISA kit

E06F0279-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Goat F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human F- box only protein 17, FBXO17 ELISA KIT

ELI-48580h 96 Tests
EUR 824

Guinea pig F box only protein 17(FBXO17) ELISA kit

E05F0279-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Guinea pig F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig F box only protein 17(FBXO17) ELISA kit

E05F0279-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Guinea pig F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig F box only protein 17(FBXO17) ELISA kit

E05F0279-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Guinea pig F box only protein 17(FBXO17) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4857605 3 x 1.0 ug
EUR 376

Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K6558005 3 x 1.0 ug
EUR 376

FBXO17 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0764705 3 x 1.0 ug
EUR 376

Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K4857606 1.0 ug DNA
EUR 167

Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K4857607 1.0 ug DNA
EUR 167

Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K4857608 1.0 ug DNA
EUR 167

Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K6558006 1.0 ug DNA
EUR 167

Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K6558007 1.0 ug DNA
EUR 167

Fbxo17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K6558008 1.0 ug DNA
EUR 167

FBXO17 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV665294 1.0 ug DNA
EUR 514

FBXO17 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV665295 1.0 ug DNA
EUR 572

FBXO17 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV665296 1.0 ug DNA
EUR 572

FBXO17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K0764706 1.0 ug DNA
EUR 167

FBXO17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K0764707 1.0 ug DNA
EUR 167

FBXO17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K0764708 1.0 ug DNA
EUR 167

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 277
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 277

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 277

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 277

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 277
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 277

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 277

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 277

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 277

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 277

Anti-Anti-DDB1 Antibody

A00333 100uL
EUR 455
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

4-AEA465Hu
  • EUR 5698.00
  • EUR 3011.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody)

ELK8071 1 plate of 96 wells
EUR 432
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti- ZNF660 antibody

ABD2410 100 ug
EUR 438

Anti-STAT5B Antibody

A1753-100
EUR 479

Anti-CREB1 Antibody

A1754-100
EUR 479

Anti-COX7B Antibody

A1756-100
EUR 479

Anti-COX6B1 Antibody

A1757-100
EUR 479

Anti-COX7B2 Antibody

A1758-100
EUR 479

Anti-COX19 Antibody

A1759-100
EUR 479

Anti-AIMP2 Antibody

A1760-100
EUR 479

Anti-NFKBIE Antibody

A1762-100
EUR 479

Anti-NFKBID Antibody

A1764-100
EUR 479

Anti-APIP Antibody

A1766-100
EUR 479

Anti-BAG1 Antibody

A1768-100
EUR 479

Anti-IL10RA Antibody

A1770-100
EUR 479

Anti-IL10RB Antibody

A1771-100
EUR 479

Anti-IL12RB1 Antibody

A1772-100
EUR 479

Anti-IL13RA1 Antibody

A1773-100
EUR 479

Anti-IL13RA2 Antibody

A1774-100
EUR 479

Anti-IL17RC Antibody

A1775-100
EUR 479

Anti-IL18R1 Antibody

A1776-100
EUR 479

Anti-IL1R1 Antibody

A1777-100
EUR 479

Anti- TauD Antibody

A1804-100
EUR 370

Anti- TauD Antibody

A1804-30T
EUR 146

Anti-KRT20 Antibody

A1859-100
EUR 403

Anti-PGR Antibody

A1860-100
EUR 403

Anti-HSPA9 Antibody

A1861-100
EUR 403

Anti-ERBB4 Antibody

A1862-100
EUR 403

Anti-CA12 Antibody

A1865-100
EUR 403

Anti-TPD52 Antibody

A1867-100
EUR 403

Anti-STRADA Antibody

A1868-100
EUR 403

Anti-CD276 Antibody

A1869-100
EUR 403

Anti-ICT1 Antibody

A1872-100
EUR 403

Anti-OCIAD1 Antibody

A1873-100
EUR 403

Anti-BRINP1 Antibody

A1874-100
EUR 403

Anti-WT1 Antibody

A1875-100
EUR 403

Anti-SART3 Antibody

A1879-100
EUR 403

Anti-RRBP1 Antibody

A1880-100
EUR 403

Anti-KIAA1524 Antibody

A1881-100
EUR 403

Anti-ENO2 Antibody

A1883-100
EUR 403

Anti-GPC3 Antibody

A1884-100
EUR 403

Anti-ACP1 Antibody

A1885-100
EUR 403

Anti-Elafin Antibody

A1887-100
EUR 403

Anti-AVEN Antibody

A1891-100
EUR 403

Furthermore, the dual-luciferase reporter gene test revealed that the area 3′-untranslated (UTR) endothelin A receptor (Ednra) MRNA contains a binding site for MMU-MIR-1929-3P. Collectively, our data shows that MCMV infection can increase blood pressure and reduce MMU-MIR-1929-3P expression in C57BL / 6. In addition, we find that MMU-MIR-1929-3P targets 3 ‘UTR from MRNA Ednra. Conclusion This new regulation axis can help develop a new approach to clinical prevention and control eh.

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