Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138 Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways

Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138 Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways

Regulation of the epidermal growth factor (EGF) receptor (EGFR) signaling is essential for the replication of human cytomegalovirus (HCMV) and the latency and reactivation in CD34 + hematopoietic progenitor cells. HCMV microRNAs (miRNAs) provide a means to modulate the signal is activated by EGF through targeting EGFR signaling pathway components.

Here, we show that miR-US5-2 HCMV immediate critical downregulates EGFR GAB1 adapter proteins that mediate sustained activation and signals through phosphatidylinositol 3-kinase (PI3K) and MEK / extracellular signal-regulated kinase (ERK) pathway and cell proliferation in response to EGF. UL138 HCMV expression is regulated by the transcription factor early growth response gene 1 (EGR1) downstream of EGFR-induced MEK / ERK signaling. We show that by targeting GAB1 and smoothes the MEK / ERK signaling, mir-US5-2 indirectly regulating the expression EGR1 and UL138, which implicates critical miRNA regulation latency.IMPORTANCE HCMV Human cytomegalovirus (HCMV) causes significant illness in immunocompromised individuals, including transplant patients.

HCMV establishes latency in the hematopoietic stem cells in the bone marrow. The mechanisms that regulate the latency and reactivation of viral replication is complex and not fully understood. HCMV-encoded miRNAs are small regulatory RNA that reduces expression of the protein. In this study, we found that HCMV miRNA miR-US5-2 targeting the epidermal growth factor receptor (EGFR) protein GAB1 adapter that directly affect downstream cellular signaling pathways activated by EGF.

As a result, mir-US5-2 block EGF-mediated proliferation of human fibroblasts. early growth response gene 1 (EGR1) is a transcription factor activated by EGFR signaling that regulates the expression of HCMV UL138. We show that miR-UL138 US5-2 regulates expression via downregulation GAB1-mediated signaling pathways that lead to the expression of EGR1. These data demonstrate that miR-US5-2, through downregulation of GAB1, can play an important role during the reactivation from latency by reducing the proliferation and expression of UL138.

 Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138 Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways
Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138 Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways

early diagnosis and successful treatment of cytomegalovirus peritonitis in children with primary nephrotic syndrome: a case series and review of the literature

Cytomegalovirus (CMV) is a major pathogen in immunocompromised population and CMV infections in immunocompromised patients cause of morbidity and mortality are quite large. Common clinical manifestations of CMV infection is pneumonia, hepatitis, colitis and so on, while CMV without intestinal perforation peritonitis rarely occurs. Reviewing the literature, CMV peritonitis in patients with nephrotic syndrome (NS) has not been reported. Only four cases of peritonitis CMV without bowel perforation reported in adults with other illnesses.

Two cases were diagnosed by reverse-transcription polymerase chain reaction (RT-PCR) of ascites while two other cases with histopathological examination of peritoneal tissue. We report four cases of primary nephrotic syndrome complicated with CMV peritonitis. Four cases were all diagnosed by RT-PCR from ascites (659-455000 copies / mL).

pTAL- p53- Reporter- Luc

PVT10822 2 ug
EUR 301

Rev-CEM-Luc HIV Reporter Cells

HRC-6 - Ask for price

Lenti-hTERT virus

G200 10 ml
EUR 811

Lenti-Bmi1 Virus

LV610 10 ml
EUR 811

Lenti-CDK4 Virus

LV611 10 ml
EUR 811

Rev-A3R5-GFP/Luc HIV Reporter Cells

HRC-2 - Ask for price

Rev-CEM-GFP/Luc HIV Reporter Cells

HRC-5 - Ask for price

Human Aminoadipate Semialdehyde Phosphopantetheinyl Transferase (AASDHPPT) ELISA Kit

DLR-AASDHPPT-Hu-48T 48T
EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Human Aminoadipate Semialdehyde Phosphopantetheinyl Transferase (AASDHPPT) in samples from tissue homogenates or other biological fluids.

Human Aminoadipate Semialdehyde Phosphopantetheinyl Transferase (AASDHPPT) ELISA Kit

DLR-AASDHPPT-Hu-96T 96T
EUR 673
Description: A sandwich quantitative ELISA assay kit for detection of Human Aminoadipate Semialdehyde Phosphopantetheinyl Transferase (AASDHPPT) in samples from tissue homogenates or other biological fluids.

Human Aminoadipate Semialdehyde Phosphopantetheinyl Transferase (AASDHPPT) ELISA Kit

RD-AASDHPPT-Hu-48Tests 48 Tests
EUR 521

Human Aminoadipate Semialdehyde Phosphopantetheinyl Transferase (AASDHPPT) ELISA Kit

RD-AASDHPPT-Hu-96Tests 96 Tests
EUR 723

Human Aminoadipate Semialdehyde Phosphopantetheinyl Transferase (AASDHPPT) ELISA Kit

RDR-AASDHPPT-Hu-48Tests 48 Tests
EUR 544

Human Aminoadipate Semialdehyde Phosphopantetheinyl Transferase (AASDHPPT) ELISA Kit

RDR-AASDHPPT-Hu-96Tests 96 Tests
EUR 756

AAV2-Luc Control Virus

AAV-320 50 ?L
EUR 1018
Description: Luciferase control virus of AAV serotype 2.

AAV1-Luc Control Virus

AAV-321 50 ?L
EUR 1018
Description: Luciferase control virus of AAV serotype 1.

AAV3-Luc Control Virus

AAV-323 50 ?L
EUR 1018
Description: Luciferase control virus of AAV serotype 3.

AAV4-Luc Control Virus

AAV-324 50 ?L
EUR 1018
Description: Luciferase control virus of AAV serotype 4.

AAV5-Luc Control Virus

AAV-325 50 ?L
EUR 1018
Description: Luciferase control virus of AAV serotype 5.

AAV6-Luc Control Virus

AAV-326 50 ?L
EUR 1018
Description: Luciferase control virus of AAV serotype 6.

Lenti-hTERT Antisense virus

G201 10 ml
EUR 735

Lenti-hTERT-Neo Virus

G204 10 ml
EUR 811

Lenti-Myc T58A Virus

G217 10 ml
EUR 811

Lenti-p53 siRNA Virus

G219 10 ml
EUR 811

Lenti-Ras V12 Virus

G221 10 ml
EUR 811

Lenti-Rb siRNA Virus

G223 10 ml
EUR 811

Mouse Actc Differentiation Reporter (pGreenZeo, Virus)

SR10010VA-1 >2 x 10^6 IFUs
EUR 755

Human Tnnt2 Differentiation Reporter (pGreenZeo, Virus)

SR10012VA-1 >2 x 10^6 IFUs
EUR 755

Mouse Tnnt2 Differentiation Reporter (pGreenZeo, Virus)

SR10013VA-1 >2 x 10^6 IFUs
EUR 755

Mouse SM22a Differentiation Reporter (pGreenZeo, Virus)

SR10014VA-1 >2 x 10^6 IFUs
EUR 755

Human GFAP Differentiation Reporter (pGreenZeo, Virus)

SR10015VA-1 >2 x 10^6 IFUs
EUR 755

Mouse GFAP Differentiation Reporter (pGreenZeo, Virus)

SR10016VA-1 >2 x 10^6 IFUs
EUR 755

Human CD11b Differentiation Reporter (pGreenZeo, Virus)

SR10017VA-1 >2 x 10^6 IFUs
EUR 755

Mouse EMR1 Differentiation Reporter (pGreenZeo, Virus)

SR10018VA-1 >2 x 10^6 IFUs
EUR 755

Mouse Col2a1 Differentiation Reporter (pGreenZeo, Virus)

SR1001VA-1 >2 x 10^6 IFUs
EUR 755

Mouse CD44 Differentiation Reporter (pGreenZeo, Virus)

SR10020VA-1 >2 x 10^6 IFUs
EUR 755

Human BM88 Differentiation Reporter (pGreenZeo, Virus)

SR10021VA-1 >2 x 10^6 IFUs
EUR 755

Mouse Camk2a Differentiation Reporter (pGreenZeo, Virus)

SR10022VA-1 >2 x 10^6 IFUs
EUR 755

Mouse GAD67 Differentiation Reporter (pGreenZeo, Virus)

SR10023VA-1 >2 x 10^6 IFUs
EUR 755

Rat NSE Differentiation Reporter (pGreenZeo, Virus)

SR10024VA-1 >2 x 10^6 IFUs
EUR 755

Mouse MBP Differentiation Reporter (pGreenZeo, Virus)

SR10026VA-1 >2 x 10^6 IFUs
EUR 755

Human Opsin Differentiation Reporter (pGreenZeo, Virus)

SR10027VA-1 >2 x 10^6 IFUs
EUR 755

Human Insulin Differentiation Reporter (pGreenZeo, Virus)

SR10028VA-1 >2 x 10^6 IFUs
EUR 755

Human LCK Differentiation Reporter (pGreenZeo, Virus)

SR10032VA-1 >2 x 10^6 IFUs
EUR 755

Rat Nestin Differentiation Reporter (pGreenZeo, Virus)

SR10034VA-1 >2 x 10^6 IFUs
EUR 755

Human Nestin Differentiation Reporter (pGreenZeo, Virus)

SR10035VA-1 >2 x 10^6 IFUs
EUR 755

Mouse ALBP Differentiation Reporter (pGreenZeo, Virus)

SR10036VA-1 >2 x 10^6 IFUs
EUR 755

Human NGN3 Differentiation Reporter (pGreenZeo, Virus)

SR10037VA-1 >2 x 10^6 IFUs
EUR 755

Human PDX1 Differentiation Reporter (pGreenZeo, Virus)

SR10039VA-1 >2 x 10^6 IFUs
EUR 755

Human Osteocalcin Differentiation Reporter (pGreenZeo, Virus)

SR1003VA-1 >2 x 10^6 IFUs
EUR 755

Mouse PDX1 Differentiation Reporter (pGreenZeo, Virus)

SR10040VA-1 >2 x 10^6 IFUs
EUR 755

Human MAP2 Differentiation Reporter (pGreenZeo, Virus)

SR10047VA-1 >2 x 10^6 IFUs
EUR 755

Human FABP7 Differentiation Reporter (pGreenZeo, Virus)

SR10048VA-1 >2 x 10^6 IFUs
EUR 755

Human ACTC Differentiation Reporter (pGreenZeo, Virus)

SR10049VA-1 >2 x 10^6 IFUs
EUR 755

Human B29 Differentiation Reporter (pGreenZeo, Virus)

SR1004VA-1 >2 x 10^6 IFUs
EUR 755

Mouse Myogenin Differentiation Reporter (pGreenZeo, Virus)

SR10050VA-1 >2 x 10^6 IFUs
EUR 755

Human GFAP Differentiation Reporter (pRedZeo, Virus)

SR10051VA-1 >2 x 10^6 IFUs
EUR 755

Mouse B29 Differentiation Reporter (pGreenZeo, Virus)

SR1005VA-1 >2 x 10^6 IFUs
EUR 755

Human NKX2.5 Differentiation Reporter (pGreenZeo, virus)

SR10067VA-1 >2 x 10^6 IFUs
EUR 755

Mouse CD8 Differentiation Reporter (pGreenZeo, Virus)

SR1006VA-1 >2 x 10^6 IFUs
EUR 755

Mouse CD68 Differentiation Reporter (pGreenZeo, Virus)

SR1008VA-1 >2 x 10^6 IFUs
EUR 755

Human CD2 Differentiation Reporter (pGreenZeo, Virus)

SR1009VA-1 >2 x 10^6 IFUs
EUR 755

Oct4 CR4-pGreenFire Response Reporter (virus)

SR20070-VA-1 >2 x 10^6 IFUs
EUR 735

Steady-Luc Firefly HTS Assay Kit (10x100 ml)

30028-3 1KIT
EUR 3145
Description: Minimum order quantity: 1 unit of 1KIT

AASDHPPT 3'UTR Luciferase Stable Cell Line

TU000028 1.0 ml
EUR 1521

Aasdhppt 3'UTR Luciferase Stable Cell Line

TU200027 1.0 ml Ask for price

Aasdhppt 3'UTR GFP Stable Cell Line

TU250027 1.0 ml Ask for price

AASDHPPT 3'UTR GFP Stable Cell Line

TU050028 1.0 ml
EUR 1521

NF-kB/293/GFP-Luc Transcriptional Reporter Cell Line

TR860A-1 >2 x 10^6 cells
EUR 3263

Lenti-EF1α-hTERT Virus

G706 10 ml
EUR 912

Lenti-Bmi1 Virus, High Titer

LV608 5 x 20 ul
EUR 1521

Lenti-CDK4 Virus, High Titer

LV609 5 x 20 ul
EUR 1521

Lenti-hTERT Virus, High Titer

LV615 5 x 20 ul
EUR 1521

Aasdhppt/ Rat Aasdhppt ELISA Kit

ELI-11895r 96 Tests
EUR 886

Human MLC-2v Differentiation Reporter (pGreenZeo, Virus)

SR10011VA-1 >2 x 10^6 IFUs
EUR 755

Human GFAP Differentiation Reporter (pGreenZeo, Virus) Puro

SR10015VA-P >2 x 10^6 IFUs
EUR 755

Mouse IBA-1 Differentiation Reporter (pGreenZeo, Virus)

SR10019VA-1 >2 x 10^6 IFUs
EUR 755

Mouse Alpha-Tubulin Differentiation Reporter (pGreenZeo, Virus)

SR10025VA-1 >2 x 10^6 IFUs
EUR 755

Human SPP-1 Differentiation Reporter (pGreenZeo, Virus)

SR1002VA-1 >2 x 10^6 IFUs
EUR 755

Human Keratin 14 Differentiation Reporter (pGreenZeo, Virus)

SR10038VA-1 >2 x 10^6 IFUs
EUR 755

Human Doublecortin (DCX) Differentiation Reporter (pGreenZeo, Virus)

SR10041VA-1 >2 x 10^6 IFUs
EUR 755

Human HLA-DRa Differentiation Reporter (pGreenZeo, Virus)

SR1007VA-1 >2 x 10^6 IFUs
EUR 755

AASDHPPT antibody

70R-35912 100 ug
EUR 327
Description: Rabbit polyclonal AASDHPPT antibody

AASDHPPT Antibody

ABD4134 100 ug
EUR 438

anti-AASDHPPT

YF-PA20382 50 ul
EUR 363
Description: Mouse polyclonal to AASDHPPT

anti-AASDHPPT

YF-PA20383 50 ug
EUR 363
Description: Mouse polyclonal to AASDHPPT

anti-AASDHPPT

YF-PA26532 50 ul
EUR 334
Description: Mouse polyclonal to AASDHPPT

AASDHPPT antibody

70R-2638 50 ug
EUR 467
Description: Rabbit polyclonal AASDHPPT antibody raised against the C terminal of AASDHPPT

AASDHPPT Antibody

DF4134 200ul
EUR 304
Description: AASDHPPT Antibody detects endogenous levels of total AASDHPPT.

AASDHPPT Antibody

1-CSB-PA983505
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against AASDHPPT. Recognizes AASDHPPT from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

AASDHPPT Antibody

CSB-PA299054-
EUR 335
Description: A polyclonal antibody against AASDHPPT. Recognizes AASDHPPT from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

AASDHPPT Antibody

CSB-PA299054-100ul 100ul
EUR 316
Description: A polyclonal antibody against AASDHPPT. Recognizes AASDHPPT from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

AASDHPPT Antibody

1-CSB-PA648080
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AASDHPPT. Recognizes AASDHPPT from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000

AASDHPPT Antibody

1-CSB-PA865121LA01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AASDHPPT. Recognizes AASDHPPT from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

AASDHPPT Antibody

1-CSB-PA919003
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against AASDHPPT. Recognizes AASDHPPT from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

AASDHPPT siRNA

20-abx900055
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

AASDHPPT siRNA

20-abx906269
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

AASDHPPT siRNA

20-abx906270
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

AASDHPPT (Recombinant)

20-abx073160
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

AASDHPPT Antibody

34753-100ul 100ul
EUR 252

AASDHPPT Antibody

34753-50ul 50ul
EUR 187

Lenti-HPV-16 E6/E7 Virus

G268 10 ml
EUR 735

Lenti-Myc T58A Virus, High Titer

LV618 5 x 20 ul
EUR 1521

Lenti-p53 siRNA Virus, High Titer

LV619 5 x 20 ul
EUR 1521

Lenti-Ras V12 Virus, High Titer

LV620 5 x 20 ul
EUR 1521

Lenti-Rb siRNA Virus, High Titer

LV621 5 x 20 ul
EUR 1521

Lenti-hTERT-Neo Virus, High Titer

LV622 5 x 20 ul
EUR 1521

Lenti-EF1α-hTERT-Hygro Virus

LV631 10 ml
EUR 1059

pMIR-Reporter-RASA1(3

PVTB00444-2a 2 ug
EUR 356

pMIR-Reporter-IL13(3

PVTB00445-2a 2 ug
EUR 356

Human E-Cadherin, CDH1 Differentiation Reporter (pGreenZeo, virus)

SR10070VA-1 >2 x 10^6 IFUs
EUR 755

Sox2 SRR2-pGreenFire Response Reporter, pre-packaged virus

SR20071-VA-1 >2 x 10^6 IFUs
EUR 735

Lenti-CMV-hTERT-RFP-2A-Puro Virus

LV625 10 ml
EUR 1059

Lenti-EF1α-hTERT Virus, High Titer

LV616 5 x 20 ul
EUR 1724

Lenti-CMV-hTERT-GFP-2A-Puro Virus

LV623 10 ml
EUR 1059

Human Alpha-Actin 2, ACTA2 Differentiation Reporter (pGreenZeo, virus)

SR10068VA-1 >2 x 10^6 IFUs
EUR 755

Anti-AASDHPPT (2C12)

YF-MA19166 100 ug
EUR 363
Description: Mouse monoclonal to AASDHPPT

AASDHPPT Blocking Peptide

33R-8756 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of AASDHPPT antibody, catalog no. 70R-2638

AASDHPPT Blocking Peptide

DF4134-BP 1mg
EUR 195

Anti-AASDHPPT antibody

PAab00024 100 ug
EUR 386

AASDHPPT cloning plasmid

CSB-CL865121HU1-10ug 10ug
EUR 233
Description: A cloning plasmid for the AASDHPPT gene.

AASDHPPT cloning plasmid

CSB-CL865121HU2-10ug 10ug
EUR 233
Description: A cloning plasmid for the AASDHPPT gene.

pCMV-SPORT6-AASDHPPT

PVT13953 2 ug
EUR 391

AASDHPPT Polyclonal Antibody

A56783 100 µg
EUR 570.55
Description: Ask the seller for details

AASDHPPT Rabbit pAb

A4909-100ul 100 ul
EUR 308

AASDHPPT Rabbit pAb

A4909-200ul 200 ul
EUR 459

AASDHPPT Rabbit pAb

A4909-20ul 20 ul
EUR 183

AASDHPPT Rabbit pAb

A4909-50ul 50 ul
EUR 223

Anti-AASDHPPT antibody

STJ116267 100 µl
EUR 277
Description: The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.

AASDHPPT Conjugated Antibody

C34753 100ul
EUR 397

anti- AASDHPPT antibody

FNab00024 100µg
EUR 548.75
Description: Antibody raised against AASDHPPT

pGL3 3'UTR reporter WT 1.3 kb CD274 Hs 3'UTR Final Plasmid

PVT17094 2 ug
EUR 325

Lenti-HPV-16 E6/E7 Virus, High Titer

LV617 5 x 20 ul
EUR 1420

pLL-CMV-GFP-T2A-Puro [Lenti-LabelerTM virus]

LL100VA-1 >2x10^6 IFUs
EUR 675

pLL-CMV-GFP-T2A-Blast [Lenti-LabelerTM virus]

LL105VA-1 >2x10^6 IFUs
EUR 675

pLL-CMV-RFP-T2A-Puro [Lenti-LabelerTM virus]

LL110VA-1 >2x10^6 IFUs
EUR 675

pLL-CMV-RFP-T2A-Blast [Lenti-LabelerTM virus]

LL115VA-1 >2x10^6 IFUs
EUR 675

pLL-CMV-BFP-T2A-Puro [Lenti-LabelerTM virus]

LL120VA-1 >2x10^6 IFUs
EUR 675

pLL-CMV-BFP-T2A-Blast [Lenti-LabelerTM virus]

LL125VA-1 >2x10^6 IFUs
EUR 675

pLL-CMV-Luciferase-T2A-Puro [Lenti-LabelerTM virus]

LL150VA-1 >2x10^6 IFUs
EUR 675

pLL-EF1a-GFP-T2A-Puro [Lenti-LabelerTM virus]

LL200VA-1 >2x10^6 IFUs
EUR 675

pLL-EF1a-GFP-T2A-Blast [Lenti-LabelerTM virus]

LL205VA-1 >2x10^6 IFUs
EUR 675

pLL-EF1a-RFP-T2A-Puro [Lenti-LabelerTM virus]

LL210VA-1 >2x10^6 IFUs
EUR 675

pLL-EF1a-RFP-T2A-Blast [Lenti-LabelerTM virus]

LL215VA-1 >2x10^6 IFUs
EUR 675

pLL-EF1a-BFP-T2A-Puro [Lenti-LabelerTM virus]

LL220VA-1 >2x10^6 IFUs
EUR 675

pLL-EF1a-BFP-T2A-Blast [Lenti-LabelerTM virus]

LL225VA-1 >2x10^6 IFUs
EUR 675

pLL-EF1a-Luciferase-T2A-Puro [Lenti-LabelerTM virus]

LL250VA-1 >2x10^6 IFUs
EUR 675

pLL-CMV-rFLuc-T2A-GFP [Lenti-LabelerTM virus]

LL300VA-1 >2x10^6 IFUs
EUR 697

Lentiviral Dual Reporter: CMV-GFP-T2A-Luciferase pre-packaged virus

BLIV101VA-1 >2 x10^6 IFUs
EUR 803

Lentiviral Triple Reporter: CMV-Luciferase-RFP-TK pre-packaged virus

BLIV102VA-1 >2 x10^6 IFUs
EUR 803

Lentiviral Dual Reporter: UBC-RFP-T2A-Luciferase pre-packaged virus

BLIV200VA-1 >2 x10^6 IFUs
EUR 803

Lentiviral Triple Reporter: UBC-Luciferase-RFP-TK pre-packaged virus

BLIV202VA-1 >2 x10^6 IFUs
EUR 803

Lentiviral Triple Reporter: MSCV-Luciferase-RFP-TK pre-packaged virus

BLIV302VA-1 >2 x10^6 IFUs
EUR 803

BLIV 2.0 Reporter: CMV-Luciferase-EF1a-copGFP Pre-packaged Virus

BLIV511VA-1 >2 x10^6 IFUs
EUR 803

Human MLC-2v Differentiation Reporter (pGreenZeo, Virus), EF1-Neo Marker

SR10011VA-N >2 x 10^6 IFUs
EUR 755

SKOV-3/Luc Cell Line

AKR-232 1 vial
EUR 572
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

Aasdhppt sgRNA CRISPR Lentivector (Rat) (Target 3)

K6259704 1.0 ug DNA
EUR 154

We mainly discuss the diagnosis and treatment of CMV without intestinal perforation peritonitis.Human cytomegalovirus (HCMV) is a double-stranded DNA virus widely infected humans. Circular RNAs (circRNAs) is a non-coding RNA with most functions remain unknown, and the effects of HCMV infection in the host circRNA productive transcription remains unclear. In this study, we profiled 283 hosts a significant circRNAs amended by the productive infection of HCMV in human embryonic lung fibroblast (helf) by RNA deep sequencing and bioinformatics analysis. Among other things, circSP100, circMAP3K1, circPLEKHM1, and circTRIO validated for transcription and their sequence.

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