Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Mother’s infarction (MFI) and Masif Fibrin Perive (MPFD) deposition (MPFD) are unusual, related to the condition of the secondary placenta of trophoblastic cell damage. The etiology is unknown but MPFD / MFI is associated with adverse obstetric results and a significant risk of repeatment. Case Report: We report the MPFD / MFI case related to placentitis Cytomegalovirus (CMV). A 27-year-old mother gave birth to a man’s fetus born with a postmortem diagnosis of default CMV.

The placenta shows limfohistiocial villitis with isolated CMV inclusion, in combination with MFI. Villitis has an intermediary feature between unclean cmv placentitis and ethiological villitis (Vue). Conclusion: Vue is considered a reaction of an anti-fetal immune mother who resembles the refusal of allograft. We postulate that viral infections in our case may have triggered this immune response, considering that CMV antigens are known to be crossing with some human antigens, especially HLA. The next trophoblastic cell damage can then lead to MFI / MFPD.

Hemolytic uremic syndrome and atypical nephrotic syndrome associated with cytomegalovirus infection

Atypical hemolytic uremic syndrome (ahus) is a rare disease. It is produced from the disregulation of alternative complementary pathways on the cell surface which causes endothelial damage. Increasing evidence evidence, this disorder is for mutations in the complementary regulator gene or with autoantibodies to complementary factors. This mutation has incomplete penetration and variable phenotypes.

Cytomegalovirus (CMV) is endemic throughout the world, and the incidence of severe CMV disease in immunocompetent adults seems to be greater than previously thought. Ahus and nephrotic syndrome associated with CMV infection rarely occur. The identification of triggers for the manifestation of the ahus in patients who are vulnerable genetics is very important because this allows faster clinical treatment and improvement initiations. We reported a case of a man with the removal of homozygous CFHR3-1 whose initial presentation was ahus and nephrotic syndrome associated with CMV infection.

IgA binds epitop glycoprotein B and neutralizes human cytomegalovirus

Human Cytomegalovirus (HCMV) is a pathogen everywhere that has the potential for pathogens in immunosuppression individuals and pregnant women during primary infections. HCMV Envelope Glycoprotein B (GB) facilitates virus entries into all types of cells and induces strong immune responses. Epitope AD-2 is a very preserved GB Linear GB epitope and the critical target for antibodies, only 50% of seropositive individuals that make IgG antibodies to this site and the rib response has not been fully investigated.

This study aims to compare IGG and IGA responses to GB and Epitop AD-2 in individuals who are exposed to naturally and those who receive the recombinant Ajuvant GB / MF59 vaccine. Thus, seropositive individual vaccination increases the existing IGA and GB IGG levels and induces the rib response and specific IGG de Novo GB on seronegative receivers. The existing IgG response and AD-2 ribs were driven by vaccination but the response of De Novo AD-2 was not detected. Individuals exposed naturally have the dominant IgG response to GB and AD-2 compared to weaker rib responses and variables, although significant rib response to AD-2 was observed in the ASI ASI sample.

All antibodies tie the AD-2 contain a light chain of kappa while the use of a balanced capa / lambda light chain is found for those who bind to GB. The V-region matches the specific recombinant IGG AD-2 and ribs are bound to GB and AD-2 and neutralize HCMV infection in vitro. Overall, this result shows that even though the human IGG response dominates, class IGA antibodies against AD-2 are significant components of breast milk that can function to protect neonates from HCMV.

Cytomegalovirus After a kidney transplant in 2020: moving towards personalized prevention

Cytomegalovirus (CMV) – Close complications after kidney transplants remain a substantial challenge. Instead of applying a preventive strategy to all risky patients, we can now adjust our strategies at the individual patient level. The prophylaxis of antivirus or strict pre-emptive strategies may be optimal for patients with the highest risk for CMV, while lower risk patients can be profitable especially from pre-emptive monitoring and therapeutic administration only if needed.

CMV Special T-Testing may be useful to improve the determination of CMV risk in pre-transplants, and to guide decisions about the need for antivirus therapy or duration. Immunosupressive regimens including the target of the Rapamycin mammal inhibitor reduces the risk of CMV and thus can be an interesting choice in some patients. The new antivirus agent further expanded our therapy arsenal in the near future, and the prospect of CMV vaccination and remove cell therapy seems to be on the horizon.

Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Cytomegalovirus Pre-Transplant Immunity and Risk of Viral Reactivation After Lung Transplantation: Prospective Cohort Study

Cytomegalovirus (CMV) remains a significant burden on the recipient of the lung transplant. Disadvantages in the immunity of the TP-transplant increases the risk of complications related to CMV. However, it is not clear if the underlying pre-transplant immunity increases risk. To assess this, we recruit 39 lung transplant patients and do quantiferon-CMV in their peripheral blood. More than a third of prospective cmv-seropositive transplant receivers are non-imun-reactive CMV (CMV-NIR) pre-transplant.

HBA Polyclonal Antibody

ABP58750-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

HBA Polyclonal Antibody

ABP58750-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

HBA Polyclonal Antibody

ABP58750-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

Hba Polyclonal Antibody

A53679 100 µg
EUR 570.55
Description: The best epigenetics products

Hba Antibody, HRP conjugated

1-CSB-PA010147LB01MO
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is HRP conjugated. Tested in the following application: ELISA

Hba Antibody, FITC conjugated

1-CSB-PA010147LC01MO
  • EUR 317.00
  • EUR 335.00
  • 100ug
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Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA

Hba Antibody, Biotin conjugated

1-CSB-PA010147LD01MO
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is Biotin conjugated. Tested in the following application: ELISA

Human Brain Astrocytes (HBA)

HMP202 500,000+ cells - Frozen
EUR 1080

Hba-x sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3266403 1.0 ug DNA
EUR 154

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K3332403 1.0 ug DNA
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K3179403 1.0 ug DNA
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K6915803 1.0 ug DNA
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Mouse Hemoglobin subunit alpha (Hba)

1-CSB-YP010147MO
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Description: Recombinant Mouse Hemoglobin subunit alpha(Hba) expressed in Yeast

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1-CSB-EP010147MO
  • EUR 505.00
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Description: Recombinant Mouse Hemoglobin subunit alpha(Hba) expressed in E.coli

Hemoglobin Subunit Alpha (Hba) Antibody

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  • EUR 411.00
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Hba Polyclonal Antibody, HRP Conjugated

A53680 100 µg
EUR 570.55
Description: kits suitable for this type of research

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EUR 570.55
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HBA ELISA Kit (Bovine) (OKEH03848)

OKEH03848 96 Wells
EUR 779
Description: Description of target: Involved in oxygen transport from the lung to the various peripheral tissues.;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.59 ng/mL

HBA ELISA Kit (Mouse) (OKEH05810)

OKEH05810 96 Wells
EUR 662
Description: Description of target: Involved in oxygen transport from the lung to the various peripheral tissues. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.84 ng/mL

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ELA-E0517r 96 Tests
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ELA-E0517m 96 Tests
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2-Propyl-β-D-glucuronide, 2 mg

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K3266407 1.0 ug DNA
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2 M NaCl

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EUR 59

IL-2 Interleukin-2 Human Recombinant Protein, His Tag

PROTP60568-2 Regular: 10ug
EUR 317
Description: Interleukin-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 133 amino acids fragment (21-153) having a molecular weight of 20kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. _x000D_ The IL-2 His is purified by proprietary chromatographic techniques._x000D_

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Nori® Chicken Netrin-2 ELISA Kit (2 plates)

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Nori® Human Tie-2 ELISA Kit (2 plates)

GR106458-2 2 x 96-well
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Nori® Human TIMP-2 ELISA Kit (2 plates)

GR106460-2 2 x 96-well
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Nori® Human Trappin-2 ELISA Kit (2 plates)

GR106467-2 2 x 96-well
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GR114008-2 2 x 96-well
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GR114026-2 2 x 96-well
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Hba-x sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3266402 1.0 ug DNA
EUR 154

Hba-x sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3266404 1.0 ug DNA
EUR 154

Hba-a1 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3332402 1.0 ug DNA
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Hba-a1 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3332404 1.0 ug DNA
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Hba-a2 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3179402 1.0 ug DNA
EUR 154

Hba-a2 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3179404 1.0 ug DNA
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Hba-a2 sgRNA CRISPR Lentivector (Rat) (Target 1)

K6915802 1.0 ug DNA
EUR 154

Hba-a2 sgRNA CRISPR Lentivector (Rat) (Target 3)

K6915804 1.0 ug DNA
EUR 154

Hba-a2 Protein Vector (Rat) (pPB-C-His)

PV272334 500 ng
EUR 603

Hba-a2 Protein Vector (Rat) (pPB-N-His)

PV272335 500 ng
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Hba-a2 Protein Vector (Rat) (pPM-C-HA)

PV272336 500 ng
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Hba-a2 Protein Vector (Rat) (pPM-C-His)

PV272337 500 ng
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Hba-a1 Protein Vector (Mouse) (pPB-C-His)

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Hba-a1 Protein Vector (Mouse) (pPB-N-His)

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EUR 603

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PV187993 500 ng
EUR 603

Hba-a2 Protein Vector (Mouse) (pPB-C-His)

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EUR 603

Hba-a2 Protein Vector (Mouse) (pPM-C-HA)

PV187996 500 ng
EUR 603

Hba-a2 Protein Vector (Mouse) (pPM-C-His)

PV187997 500 ng
EUR 603

Hba-x Protein Vector (Mouse) (pPB-C-His)

PV187998 500 ng
EUR 603

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PV187999 500 ng
EUR 603

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PV188000 500 ng
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Hba-a2 3'UTR GFP Stable Cell Line

TU255653 1.0 ml Ask for price

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BMP-2 Bone Morphogenetic Protein-2 Human Recombinant Protein, Monomer

PROTP12643-2 Regular: 20ug
EUR 317
Description: Bone Morphogenetic Protein-2 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, Polypeptide chain containing 115 amino acids (283-396) and having a molecular mass of 13009 Dalton. ;The BMP-2 is purified by proprietary chromatographic techniques.

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GR113081-2 2 x 96-well
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GR106163-2 2 x 96-well
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GR106188-2 2 x 96-well
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59423-2 2 EA
EUR 192.24

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G065-2 200 reactions
EUR 167

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GR111143-2 2 x 96-well
EUR 832

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GR106503-2 2 x 96-well
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GR106504-2 2 x 96-well
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Nori Equine MMP-3/TIMP-2 Complex ELISA Kit (2 plates)

GR106506-2 2 x 96-well
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The CMV-NIR status is associated with the incidence of CMV reactivation transplantation which is significantly higher, indicating that the immunity of CMV dysfunctional in prospective lung transplant recipients is associated with an increased risk of viral viral-transplant reactivation.
Keywords: cytomegalovirus; T-cell immunity; solid organ transplant; Virus reactivation.

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