Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Mother’s infarction (MFI) and Masif Fibrin Perive (MPFD) deposition (MPFD) are unusual, related to the condition of the secondary placenta of trophoblastic cell damage. The etiology is unknown but MPFD / MFI is associated with adverse obstetric results and a significant risk of repeatment. Case Report: We report the MPFD / MFI case related to placentitis Cytomegalovirus (CMV). A 27-year-old mother gave birth to a man’s fetus born with a postmortem diagnosis of default CMV.

The placenta shows limfohistiocial villitis with isolated CMV inclusion, in combination with MFI. Villitis has an intermediary feature between unclean cmv placentitis and ethiological villitis (Vue). Conclusion: Vue is considered a reaction of an anti-fetal immune mother who resembles the refusal of allograft. We postulate that viral infections in our case may have triggered this immune response, considering that CMV antigens are known to be crossing with some human antigens, especially HLA. The next trophoblastic cell damage can then lead to MFI / MFPD.

Hemolytic uremic syndrome and atypical nephrotic syndrome associated with cytomegalovirus infection

Atypical hemolytic uremic syndrome (ahus) is a rare disease. It is produced from the disregulation of alternative complementary pathways on the cell surface which causes endothelial damage. Increasing evidence evidence, this disorder is for mutations in the complementary regulator gene or with autoantibodies to complementary factors. This mutation has incomplete penetration and variable phenotypes.

Cytomegalovirus (CMV) is endemic throughout the world, and the incidence of severe CMV disease in immunocompetent adults seems to be greater than previously thought. Ahus and nephrotic syndrome associated with CMV infection rarely occur. The identification of triggers for the manifestation of the ahus in patients who are vulnerable genetics is very important because this allows faster clinical treatment and improvement initiations. We reported a case of a man with the removal of homozygous CFHR3-1 whose initial presentation was ahus and nephrotic syndrome associated with CMV infection.

IgA binds epitop glycoprotein B and neutralizes human cytomegalovirus

Human Cytomegalovirus (HCMV) is a pathogen everywhere that has the potential for pathogens in immunosuppression individuals and pregnant women during primary infections. HCMV Envelope Glycoprotein B (GB) facilitates virus entries into all types of cells and induces strong immune responses. Epitope AD-2 is a very preserved GB Linear GB epitope and the critical target for antibodies, only 50% of seropositive individuals that make IgG antibodies to this site and the rib response has not been fully investigated.

This study aims to compare IGG and IGA responses to GB and Epitop AD-2 in individuals who are exposed to naturally and those who receive the recombinant Ajuvant GB / MF59 vaccine. Thus, seropositive individual vaccination increases the existing IGA and GB IGG levels and induces the rib response and specific IGG de Novo GB on seronegative receivers. The existing IgG response and AD-2 ribs were driven by vaccination but the response of De Novo AD-2 was not detected. Individuals exposed naturally have the dominant IgG response to GB and AD-2 compared to weaker rib responses and variables, although significant rib response to AD-2 was observed in the ASI ASI sample.

All antibodies tie the AD-2 contain a light chain of kappa while the use of a balanced capa / lambda light chain is found for those who bind to GB. The V-region matches the specific recombinant IGG AD-2 and ribs are bound to GB and AD-2 and neutralize HCMV infection in vitro. Overall, this result shows that even though the human IGG response dominates, class IGA antibodies against AD-2 are significant components of breast milk that can function to protect neonates from HCMV.

Cytomegalovirus After a kidney transplant in 2020: moving towards personalized prevention

Cytomegalovirus (CMV) – Close complications after kidney transplants remain a substantial challenge. Instead of applying a preventive strategy to all risky patients, we can now adjust our strategies at the individual patient level. The prophylaxis of antivirus or strict pre-emptive strategies may be optimal for patients with the highest risk for CMV, while lower risk patients can be profitable especially from pre-emptive monitoring and therapeutic administration only if needed.

CMV Special T-Testing may be useful to improve the determination of CMV risk in pre-transplants, and to guide decisions about the need for antivirus therapy or duration. Immunosupressive regimens including the target of the Rapamycin mammal inhibitor reduces the risk of CMV and thus can be an interesting choice in some patients. The new antivirus agent further expanded our therapy arsenal in the near future, and the prospect of CMV vaccination and remove cell therapy seems to be on the horizon.

Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Cytomegalovirus Pre-Transplant Immunity and Risk of Viral Reactivation After Lung Transplantation: Prospective Cohort Study

Cytomegalovirus (CMV) remains a significant burden on the recipient of the lung transplant. Disadvantages in the immunity of the TP-transplant increases the risk of complications related to CMV. However, it is not clear if the underlying pre-transplant immunity increases risk. To assess this, we recruit 39 lung transplant patients and do quantiferon-CMV in their peripheral blood. More than a third of prospective cmv-seropositive transplant receivers are non-imun-reactive CMV (CMV-NIR) pre-transplant.

2-HBA

T7374-50mg 50mg Ask for price
Description: 2-HBA

2-HBA

T7374-5mg 5mg Ask for price
Description: 2-HBA

2-HBA

MBS3844319-100mg 100mg
EUR 825

2-HBA

MBS3844319-10mg 10mg
EUR 200

2-HBA

MBS3844319-50mg 50mg
EUR 440

2-HBA

MBS3844319-5mg 5mg
EUR 155

2-HBA

MBS3844319-5x100mg 5x100mg
EUR 3695

2-HBA

MBS3610818-100mg 100mg
EUR 380

2-HBA

MBS3610818-10mg 10mg
EUR 220

2-HBA

MBS3610818-25mg 25mg
EUR 260

2-HBA

MBS3610818-50mg 50mg
EUR 310

2-HBA

MBS3610818-5mg 5mg
EUR 200

2-HBA

MBS5758301-100mg 100mg
EUR 590

2-HBA

MBS5758301-10mg 10mg
EUR 175

2-HBA

MBS5758301-25mg 25mg
EUR 250

2-HBA

MBS5758301-50mg 50mg
EUR 380

2-HBA

MBS5758301-5mg 5mg
EUR 150

Hba (untagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2), (10ug)

MC212224 10 µg Ask for price

Hba Antibody

CAC08513-100ug 100ug
EUR 314

Hba Antibody

CAC08513-50ug 50ug
EUR 199.2

Hba Antibody

1-CSB-PA010147LA01MO
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Description: A polyclonal antibody against Hba. Recognizes Hba from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:1000-1:5000

HBA Antibody

C44049-100ul 100μl
EUR 217
Description: HBA Rabbit Polyclonal Antibody

HBA Antibody

C44049-50ul 50μl
EUR 143.5
Description: HBA Rabbit Polyclonal Antibody

Hba (GFP-tagged) - Mouse hemoglobin alpha adult chain 2 (Hba-a2), (10ug)

MG212474 10 µg Ask for price

Hba (Myc-DDK-tagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2)

MR212474 10 µg Ask for price

Hba (untagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x), (10ug)

MC201995 10 µg Ask for price

Hba (GFP-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x)

MG200927 10 µg Ask for price

Hba (Myc-DDK-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x)

MR200927 10 µg Ask for price

HBA Polyclonal Antibody

ABP58750-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

HBA Polyclonal Antibody

ABP58750-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

HBA Polyclonal Antibody

ABP58750-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

HBA Polyclonal Antibody

E11-202315 100ug/100ul
EUR 225
Description: Available in various conjugation types.

Hba Polyclonal Antibody

A53679
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  • 100 µg
  • 20 ul
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HBA Polyclonal Antibody

BT-AP09821-100ul 100ul Ask for price
Description: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

HBA Polyclonal Antibody

BT-AP09821-20ul 20ul Ask for price
Description: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

HBA Polyclonal Antibody

BT-AP09821-50ul 50ul Ask for price
Description: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

HBA Polyclonal Antibody

E44H09922 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

HBA Polyclonal Antibody

MBS8531677-01mg 0.1mg
EUR 305

HBA Polyclonal Antibody

MBS8531677-01mLAF405L 0.1mL(AF405L)
EUR 465

HBA Polyclonal Antibody

MBS8531677-01mLAF405S 0.1mL(AF405S)
EUR 465

HBA Polyclonal Antibody

MBS8531677-01mLAF610 0.1mL(AF610)
EUR 465

HBA Polyclonal Antibody

MBS8531677-01mLAF635 0.1mL(AF635)
EUR 465

HBA Polyclonal Antibody

UB-GEN-7025 100 ul
EUR 200

Anti-HBA HBA1HBA2 Antibody

A33949 100ul
EUR 380
Description: Boster Bio Anti-HBA HBA1HBA2 Antibody catalog # A33949. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Lenti ORF clone of Hba (mGFP-tagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2)

MR212474L4 10 µg Ask for price

Hba (GFP-tagged) - Mouse hemoglobin alpha, adult chain 1 (Hba-a1)

MG200921 10 µg Ask for price

Hba (untagged) - Mouse hemoglobin alpha, adult chain 1 (Hba-a1), (10ug)

MC208649 10 µg Ask for price

Human HBA ELISA Kit

ELA-E05171h 96tests
EUR 696

Lenti ORF clone of Hba (Myc-DDK-tagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2)

MR212474L3 10 µg Ask for price

Lenti ORF clone of Hba (mGFP-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x)

MR200927L4 10 µg Ask for price

Human Brain Astrocytes (HBA)

HMP202 500,000+ cells - Frozen
EUR 1296

Human Brain Astrocytes (HBA)

MBS556034-INQUIRE INQUIRE Ask for price

Human Brain Astrocytes (HBA)

MBS556035-INQUIRE INQUIRE Ask for price

Hba Antibody, HRP conjugated

1-CSB-PA010147LB01MO
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  • 100ug
  • 50ug
Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is HRP conjugated. Tested in the following application: ELISA

Hba Antibody, FITC conjugated

1-CSB-PA010147LC01MO
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  • 100ug
  • 50ug
Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA

Hba Antibody, Biotin conjugated

1-CSB-PA010147LD01MO
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  • 100ug
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Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is Biotin conjugated. Tested in the following application: ELISA

HBA Rabbit Polyclonal Antibody

ES11261-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against HBA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

HBA Rabbit Polyclonal Antibody

ES11261-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against HBA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

Hba (Myc-DDK-tagged) - Mouse hemoglobin alpha, adult chain 1 (Hba-a1)

MR200921 10 µg Ask for price

Lenti ORF clone of Hba (Myc-DDK-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x)

MR200927L3 10 µg Ask for price

Human Hemoglobin Subunit Alpha 2,HBa ELISA KIT

E4822Hu-1096T 10*96T
EUR 4122

Human Hemoglobin Subunit Alpha 2,HBa ELISA KIT

E4822Hu-48wells 48 wells
EUR 300

Human Hemoglobin Subunit Alpha 2,HBa ELISA KIT

E4822Hu-596T 5*96T
EUR 2061

Human Hemoglobin Subunit Alpha 2,HBa ELISA KIT

E4822Hu-96wells 96 wells
EUR 458

Hba-a2 sgRNA CRISPR Lentivector (Rat) (Target 2)

K6915803 1.0 ug DNA
EUR 184.8

Human Hemoglobin Subunit Alpha 2 (HBa) ELISA Kit

MBS1603203-10x96StripWells 10x96-Strip-Wells
EUR 3460

Human Hemoglobin Subunit Alpha 2 (HBa) ELISA Kit

MBS1603203-48StripWells 48-Strip-Wells
EUR 285

Human Hemoglobin Subunit Alpha 2 (HBa) ELISA Kit

MBS1603203-5x96StripWells 5x96-Strip-Wells
EUR 1750

Human Hemoglobin Subunit Alpha 2 (HBa) ELISA Kit

MBS1603203-96StripWells 96-Strip-Wells
EUR 425

Hba-x sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3266403 1.0 ug DNA
EUR 184.8

Hba-a2 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3179403 1.0 ug DNA
EUR 184.8

Hba-a1 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3332403 1.0 ug DNA
EUR 184.8

Human Hemoglobin Subunit Alpha 2, HBa GENLISA ELISA

KBH4822 1 x 96 wells
EUR 286

HBA ELISA Kit (Mouse) (OKEH05810)

OKEH05810 96 Wells
EUR 794.4
Description: Description of target: Involved in oxygen transport from the lung to the various peripheral tissues. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.84 ng/mL

HBA ELISA Kit (Bovine) (OKEH03848)

OKEH03848 96 Wells
EUR 934.8
Description: Description of target: Involved in oxygen transport from the lung to the various peripheral tissues.;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.59 ng/mL

Hba-a2 Recombinant Protein (Rat)

RP204248 100 ug Ask for price

Lenti ORF particles, Hba (GFP-tagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2), 200ul, >10^7 TU/mL

MR212474L4V 200 µl Ask for price

Rat Hemoglobin subunit alpha-1/2,HBA ELISA Kit

ELA-E0517r 96tests
EUR 756

Hba-x Recombinant Protein (Mouse)

RP140996 100 ug Ask for price

Mouse Hba-x Recombinant Protein

PROTP06467 10ug
EUR 265
Description: Mouse Hba-x Recombinant Protein expressed in E. coli with His-tag. Sequence domain: 1-142aa. Application(s): SDS-PAGE.

Lenti ORF particles, Hba (GFP-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x), 200ul, >10^7 TU/mL

MR200927L4V 200 µl Ask for price

Mouse Hemoglobin subunit alpha (Hba)

1-CSB-YP010147MO
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  • 100ug
  • 10ug
  • 1MG
  • 200ug
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  • 50ug
Description: Recombinant Mouse Hemoglobin subunit alpha(Hba) expressed in Yeast

Mouse Hemoglobin subunit alpha (Hba)

1-CSB-EP010147MO
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  • 100ug
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  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Hemoglobin subunit alpha(Hba) expressed in E.coli

Hba-a1 Recombinant Protein (Mouse)

RP140990 100 ug Ask for price

Hba-a2 Recombinant Protein (Mouse)

RP140993 100 ug Ask for price

Hemoglobin Subunit Alpha (Hba) Antibody

20-abx109857
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Hemoglobin Subunit Alpha (Hba) Antibody

abx109857-100l 100 µl
EUR 162.5

Hba Polyclonal Antibody, HRP Conjugated

A53680
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  • 100 µg
  • 50 ul
  • 100 ul

Hba Polyclonal Antibody, FITC Conjugated

A53681
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  • 100 µg
  • 50 ul
  • 100 ul

OPCD03805-10UG - HBA Recombinant Protein

OPCD03805-10UG 10ug
EUR 139

OPCD03805-50UG - HBA Recombinant Protein

OPCD03805-50UG 50ug
EUR 339

OPCD03806-10UG - HBA Recombinant Protein

OPCD03806-10UG 10ug
EUR 149

OPCD03806-50UG - HBA Recombinant Protein

OPCD03806-50UG 50ug
EUR 379

Hba Polyclonal Antibody, Biotin Conjugated

A53682
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  • 100 µg
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  • 100 ul

OPCD03805-200UG - HBA Recombinant Protein

OPCD03805-200UG 200ug
EUR 669

OPCD03806-200UG - HBA Recombinant Protein

OPCD03806-200UG 200ug
EUR 749

Lenti ORF particles, Hba (Myc-DDK-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x), 200ul, >10^7 TU/mL

MR200927L3V 200 µl Ask for price

Lenti ORF particles, Hba (Myc-DDK-tagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2), 200ul, >10^7 TU/mL

MR212474L3V 200 µl Ask for price

Lenti ORF clone of Hba (mGFP-tagged) - Mouse hemoglobin alpha, adult chain 1 (Hba-a1)

MR200921L4 10 µg Ask for price

Hba-a2 ORF Vector (Rat) (pORF)

ORF068084 1.0 ug DNA
EUR 607.2

Hba-x ORF Vector (Mouse) (pORF)

ORF047000 1.0 ug DNA
EUR 607.2

Hba-a1 ORF Vector (Mouse) (pORF)

ORF046998 1.0 ug DNA
EUR 607.2

Hba-a2 ORF Vector (Mouse) (pORF)

ORF046999 1.0 ug DNA
EUR 607.2

OKEH05810-96W - HBA ELISA Kit (Mouse)

OKEH05810-96W 96Wells
EUR 525

Human Hemoglobin Alpha,HBa ELISA KIT

E3835Hu-1096T 10*96T
EUR 4122

Human Hemoglobin Alpha,HBa ELISA KIT

E3835Hu-48wells 48 wells
EUR 300

Human Hemoglobin Alpha,HBa ELISA KIT

E3835Hu-596T 5*96T
EUR 2061

Human Hemoglobin Alpha,HBa ELISA KIT

E3835Hu-96wells 96 wells
EUR 458

OKEH03848-96W - HBA ELISA Kit (Bovine)

OKEH03848-96W 96Wells
EUR 625

Human Hemoglobin Alpha (HBa) ELISA Kit

MBS167177-10x96StripWells 10x96-Strip-Wells
EUR 3460

Human Hemoglobin Alpha (HBa) ELISA Kit

MBS167177-48StripWells 48-Strip-Wells
EUR 285

The CMV-NIR status is associated with the incidence of CMV reactivation transplantation which is significantly higher, indicating that the immunity of CMV dysfunctional in prospective lung transplant recipients is associated with an increased risk of viral viral-transplant reactivation.
Keywords: cytomegalovirus; T-cell immunity; solid organ transplant; Virus reactivation.

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