Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Mother’s infarction (MFI) and Masif Fibrin Perive (MPFD) deposition (MPFD) are unusual, related to the condition of the secondary placenta of trophoblastic cell damage. The etiology is unknown but MPFD / MFI is associated with adverse obstetric results and a significant risk of repeatment. Case Report: We report the MPFD / MFI case related to placentitis Cytomegalovirus (CMV). A 27-year-old mother gave birth to a man’s fetus born with a postmortem diagnosis of default CMV.

The placenta shows limfohistiocial villitis with isolated CMV inclusion, in combination with MFI. Villitis has an intermediary feature between unclean cmv placentitis and ethiological villitis (Vue). Conclusion: Vue is considered a reaction of an anti-fetal immune mother who resembles the refusal of allograft. We postulate that viral infections in our case may have triggered this immune response, considering that CMV antigens are known to be crossing with some human antigens, especially HLA. The next trophoblastic cell damage can then lead to MFI / MFPD.

Hemolytic uremic syndrome and atypical nephrotic syndrome associated with cytomegalovirus infection

Atypical hemolytic uremic syndrome (ahus) is a rare disease. It is produced from the disregulation of alternative complementary pathways on the cell surface which causes endothelial damage. Increasing evidence evidence, this disorder is for mutations in the complementary regulator gene or with autoantibodies to complementary factors. This mutation has incomplete penetration and variable phenotypes.

Cytomegalovirus (CMV) is endemic throughout the world, and the incidence of severe CMV disease in immunocompetent adults seems to be greater than previously thought. Ahus and nephrotic syndrome associated with CMV infection rarely occur. The identification of triggers for the manifestation of the ahus in patients who are vulnerable genetics is very important because this allows faster clinical treatment and improvement initiations. We reported a case of a man with the removal of homozygous CFHR3-1 whose initial presentation was ahus and nephrotic syndrome associated with CMV infection.

IgA binds epitop glycoprotein B and neutralizes human cytomegalovirus

Human Cytomegalovirus (HCMV) is a pathogen everywhere that has the potential for pathogens in immunosuppression individuals and pregnant women during primary infections. HCMV Envelope Glycoprotein B (GB) facilitates virus entries into all types of cells and induces strong immune responses. Epitope AD-2 is a very preserved GB Linear GB epitope and the critical target for antibodies, only 50% of seropositive individuals that make IgG antibodies to this site and the rib response has not been fully investigated.

This study aims to compare IGG and IGA responses to GB and Epitop AD-2 in individuals who are exposed to naturally and those who receive the recombinant Ajuvant GB / MF59 vaccine. Thus, seropositive individual vaccination increases the existing IGA and GB IGG levels and induces the rib response and specific IGG de Novo GB on seronegative receivers. The existing IgG response and AD-2 ribs were driven by vaccination but the response of De Novo AD-2 was not detected. Individuals exposed naturally have the dominant IgG response to GB and AD-2 compared to weaker rib responses and variables, although significant rib response to AD-2 was observed in the ASI ASI sample.

All antibodies tie the AD-2 contain a light chain of kappa while the use of a balanced capa / lambda light chain is found for those who bind to GB. The V-region matches the specific recombinant IGG AD-2 and ribs are bound to GB and AD-2 and neutralize HCMV infection in vitro. Overall, this result shows that even though the human IGG response dominates, class IGA antibodies against AD-2 are significant components of breast milk that can function to protect neonates from HCMV.

Cytomegalovirus After a kidney transplant in 2020: moving towards personalized prevention

Cytomegalovirus (CMV) – Close complications after kidney transplants remain a substantial challenge. Instead of applying a preventive strategy to all risky patients, we can now adjust our strategies at the individual patient level. The prophylaxis of antivirus or strict pre-emptive strategies may be optimal for patients with the highest risk for CMV, while lower risk patients can be profitable especially from pre-emptive monitoring and therapeutic administration only if needed.

CMV Special T-Testing may be useful to improve the determination of CMV risk in pre-transplants, and to guide decisions about the need for antivirus therapy or duration. Immunosupressive regimens including the target of the Rapamycin mammal inhibitor reduces the risk of CMV and thus can be an interesting choice in some patients. The new antivirus agent further expanded our therapy arsenal in the near future, and the prospect of CMV vaccination and remove cell therapy seems to be on the horizon.

Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Cytomegalovirus Pre-Transplant Immunity and Risk of Viral Reactivation After Lung Transplantation: Prospective Cohort Study

Cytomegalovirus (CMV) remains a significant burden on the recipient of the lung transplant. Disadvantages in the immunity of the TP-transplant increases the risk of complications related to CMV. However, it is not clear if the underlying pre-transplant immunity increases risk. To assess this, we recruit 39 lung transplant patients and do quantiferon-CMV in their peripheral blood. More than a third of prospective cmv-seropositive transplant receivers are non-imun-reactive CMV (CMV-NIR) pre-transplant.

2-HBA

T7374-5mg 5mg Ask for price
Description: 2-HBA

2-HBA

HY-103667 100mg
EUR 1068

Hba Antibody

1-CSB-PA010147LA01MO
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Description: A polyclonal antibody against Hba. Recognizes Hba from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Hba Antibody

CAC08513-100ug 100ug
EUR 314

Hba Antibody

CAC08513-50ug 50ug
EUR 199.2

Hba (untagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2), (10ug)

MC212224 10 µg Ask for price

Hba (GFP-tagged) - Mouse hemoglobin alpha adult chain 2 (Hba-a2), (10ug)

MG212474 10 µg Ask for price

Hba (Myc-DDK-tagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2)

MR212474 10 µg Ask for price

Hba (untagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x), (10ug)

MC201995 10 µg Ask for price

Hba (GFP-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x)

MG200927 10 µg Ask for price

HBA Polyclonal Antibody

E11-202315 100ug/100ul
EUR 225
Description: Available in various conjugation types.

Hba Polyclonal Antibody

A53679
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HBA Polyclonal Antibody

ABP58750-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

HBA Polyclonal Antibody

ABP58750-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

HBA Polyclonal Antibody

ABP58750-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

HBA Polyclonal Antibody

E44H09922 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Hba (Myc-DDK-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x)

MR200927 10 µg Ask for price

Lenti ORF clone of Hba (mGFP-tagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2)

MR212474L4 10 µg Ask for price

Hba (GFP-tagged) - Mouse hemoglobin alpha, adult chain 1 (Hba-a1)

MG200921 10 µg Ask for price

Hba (untagged) - Mouse hemoglobin alpha, adult chain 1 (Hba-a1), (10ug)

MC208649 10 µg Ask for price

Human Brain Astrocytes (HBA)

HMP202 500,000+ cells - Frozen
EUR 1296

Hba Antibody, HRP conjugated

1-CSB-PA010147LB01MO
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Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is HRP conjugated. Tested in the following application: ELISA

Lenti ORF clone of Hba (mGFP-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x)

MR200927L4 10 µg Ask for price

Hba Antibody, FITC conjugated

1-CSB-PA010147LC01MO
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Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA

Hba Antibody, Biotin conjugated

1-CSB-PA010147LD01MO
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Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is Biotin conjugated. Tested in the following application: ELISA

HBA Rabbit Polyclonal Antibody

ES11261-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against HBA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

HBA Rabbit Polyclonal Antibody

ES11261-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against HBA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

Lenti ORF clone of Hba (Myc-DDK-tagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2)

MR212474L3 10 µg Ask for price

Hba (Myc-DDK-tagged) - Mouse hemoglobin alpha, adult chain 1 (Hba-a1)

MR200921 10 µg Ask for price

Lenti ORF clone of Hba (Myc-DDK-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x)

MR200927L3 10 µg Ask for price

Hba-a2 sgRNA CRISPR Lentivector (Rat) (Target 2)

K6915803 1.0 ug DNA
EUR 184.8

Hba-x sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3266403 1.0 ug DNA
EUR 184.8

Hba-a2 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3179403 1.0 ug DNA
EUR 184.8

Hba-a1 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3332403 1.0 ug DNA
EUR 184.8

HBA ELISA Kit (Mouse) (OKEH05810)

OKEH05810 96 Wells
EUR 794.4
Description: Description of target: Involved in oxygen transport from the lung to the various peripheral tissues. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.84 ng/mL

Human Hemoglobin Subunit Alpha 2, HBa GENLISA ELISA

KBH4822 1 x 96 wells
EUR 286

HBA ELISA Kit (Bovine) (OKEH03848)

OKEH03848 96 Wells
EUR 934.8
Description: Description of target: Involved in oxygen transport from the lung to the various peripheral tissues.;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.59 ng/mL

Hba-a2 Recombinant Protein (Rat)

RP204248 100 ug Ask for price

Hba-x Recombinant Protein (Mouse)

RP140996 100 ug Ask for price

Mouse Hemoglobin subunit alpha (Hba)

1-CSB-YP010147MO
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Description: Recombinant Mouse Hemoglobin subunit alpha(Hba) expressed in Yeast

Mouse Hemoglobin subunit alpha (Hba)

1-CSB-EP010147MO
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Description: Recombinant Mouse Hemoglobin subunit alpha(Hba) expressed in E.coli

Hba-a1 Recombinant Protein (Mouse)

RP140990 100 ug Ask for price

Hba-a2 Recombinant Protein (Mouse)

RP140993 100 ug Ask for price

Lenti ORF particles, Hba (GFP-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x), 200ul, >10^7 TU/mL

MR200927L4V 200 µl Ask for price

Hemoglobin Subunit Alpha (Hba) Antibody

20-abx109857
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Hemoglobin Subunit Alpha (Hba) Antibody

abx109857-100l 100 µl
EUR 162.5

Hba Polyclonal Antibody, HRP Conjugated

A53680
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Hba Polyclonal Antibody, FITC Conjugated

A53681
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  • 100 µg
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OPCD03805-10UG - HBA Recombinant Protein

OPCD03805-10UG 10ug
EUR 139

OPCD03805-50UG - HBA Recombinant Protein

OPCD03805-50UG 50ug
EUR 339

OPCD03806-10UG - HBA Recombinant Protein

OPCD03806-10UG 10ug
EUR 149

OPCD03806-50UG - HBA Recombinant Protein

OPCD03806-50UG 50ug
EUR 379

Hba Polyclonal Antibody, Biotin Conjugated

A53682
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  • 100 µg
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OPCD03805-200UG - HBA Recombinant Protein

OPCD03805-200UG 200ug
EUR 669

OPCD03806-200UG - HBA Recombinant Protein

OPCD03806-200UG 200ug
EUR 749

Lenti ORF particles, Hba (GFP-tagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2), 200ul, >10^7 TU/mL

MR212474L4V 200 µl Ask for price

Rat Hemoglobin subunit alpha-1/2, HBA ELISA Kit

ELA-E0517r 96 Tests
EUR 1063.2

Lenti ORF particles, Hba (Myc-DDK-tagged) - Mouse hemoglobin X, alpha-like embryonic chain in Hba complex (Hba-x), 200ul, >10^7 TU/mL

MR200927L3V 200 µl Ask for price

Hba-a2 ORF Vector (Rat) (pORF)

ORF068084 1.0 ug DNA
EUR 607.2

Hba-x ORF Vector (Mouse) (pORF)

ORF047000 1.0 ug DNA
EUR 607.2

Lenti ORF clone of Hba (mGFP-tagged) - Mouse hemoglobin alpha, adult chain 1 (Hba-a1)

MR200921L4 10 µg Ask for price

Hba-a1 ORF Vector (Mouse) (pORF)

ORF046998 1.0 ug DNA
EUR 607.2

Hba-a2 ORF Vector (Mouse) (pORF)

ORF046999 1.0 ug DNA
EUR 607.2

Lenti ORF particles, Hba (Myc-DDK-tagged) - Mouse hemoglobin alpha, adult chain 2 (Hba-a2), 200ul, >10^7 TU/mL

MR212474L3V 200 µl Ask for price

OKEH05810-96W - HBA ELISA Kit (Mouse)

OKEH05810-96W 96Wells
EUR 525

OKEH03848-96W - HBA ELISA Kit (Bovine)

OKEH03848-96W 96Wells
EUR 625

Rabbit Anti Human SIRT6 Monoclonal Clone HBA-19

IRBAHUSIRT6HBA19C100UL each
EUR 496
Description: Rabbit Anti Human SIRT6 Monoclonal Clone HBA-19

Lenti ORF clone of Hba (Myc-DDK-tagged) - Mouse hemoglobin alpha, adult chain 1 (Hba-a1)

MR200921L3 10 µg Ask for price

Human Hemoglobin Alpha, HBa GENLISA ELISA

KBH3835 1 x 96 wells
EUR 286

Recombinant Mouse Hemoglobin subunit alpha (Hba)

CSB-YP010147MO 5707 mg Ask for price

Recombinant Mouse Hemoglobin subunit alpha (Hba)

CSB-EP010147MO 1353 mg Ask for price

Recombinant Mouse Hemoglobin subunit alpha(Hba)

AP72590 each Ask for price

Recombinant Mouse Hemoglobin subunit alpha(Hba)

AP70383 1mg
EUR 2826

Hba1 (untagged ORF) - Rat hemoglobin alpha, adult chain 2 (Hba-a2), (10 ug)

RN201010 10 µg Ask for price

Hba-a2 sgRNA CRISPR Lentivector set (Rat)

K6915801 3 x 1.0 ug
EUR 406.8

Hba-x sgRNA CRISPR Lentivector set (Mouse)

K3266401 3 x 1.0 ug
EUR 406.8

Dog HBA / Hemoglobin subunit alpha ELISA Kit

E0517d 96T
EUR 900

Pig HBA / Hemoglobin subunit alpha ELISA Kit

E0517p 96T
EUR 900

Hba-a2 sgRNA CRISPR Lentivector set (Mouse)

K3179401 3 x 1.0 ug
EUR 406.8

Hba-a1 sgRNA CRISPR Lentivector set (Mouse)

K3332401 3 x 1.0 ug
EUR 406.8

Hba-a1 (Rat) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR513383 2 nmol Ask for price

Human Hemoglobin subunit alpha, HBA ELISA Kit

ELA-E05171h 96 Tests
EUR 988.8

Mouse Hemoglobin subunit alpha, HBA ELISA Kit

ELA-E0517m 96 Tests
EUR 1038

Mouse Hemoglobin subunit alpha (Hba) ELISA Kit

RK06912 96T
EUR 280

Mouse Hemoglobin subunit alpha(HBA)ELISA Kit

YLA1329MO-48T 48T Ask for price

Mouse Hemoglobin subunit alpha(HBA)ELISA Kit

YLA1329MO-96T 96T Ask for price

Mouse Hba / Hemoglobin subunit alpha ELISA Kit

E0517m 96T
EUR 776

Hba-x (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR402733 2 nmol Ask for price

Bovine HBA/ Hemoglobin subunit alpha ELISA Kit

E0304Bo 1 Kit
EUR 630
Description: Alpha-globin,Hemoglobin alpha chain

Bovine Hemoglobin subunit alpha, HBA ELISA Kit

ELA-E0517b 96 Tests
EUR 1113.6

Canine Hemoglobin subunit alpha, HBA ELISA Kit

ELA-E0517d 96 Tests
EUR 1113.6

Bovine Hemoglobin subunit alpha (HBA) ELISA Kit

RK06911 96T
EUR 280

Canine Hemoglobin subunit alpha(HBA)ELISA Kit

YLA0127CA-48T 48T Ask for price

Canine Hemoglobin subunit alpha(HBA)ELISA Kit

YLA0127CA-96T 96T Ask for price

Bovine Hemoglobin subunit alpha(HBA)ELISA Kit

YLA0005BO-48T 48T Ask for price

Bovine Hemoglobin subunit alpha(HBA)ELISA Kit

YLA0005BO-96T 96T Ask for price

Bovine HBA / Hemoglobin subunit alpha ELISA Kit

E0517b 96T
EUR 900

Hba-a1 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR402734 2 nmol Ask for price

Hba-a2 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR402750 2 nmol Ask for price

Chicken Hemoglobin subunit alpha, HBA ELISA Kit

ELA-E0517c 96 Tests
EUR 1113.6

Porcine Hemoglobin subunit alpha, HBA ELISA Kit

ELA-E0517p 96 Tests
EUR 1113.6

Porcine Hemoglobin subunit alpha(HBA)ELISA Kit

YLA0356PO-48T 48T Ask for price

Porcine Hemoglobin subunit alpha(HBA)ELISA Kit

YLA0356PO-96T 96T Ask for price

Hba-ps4 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR404899 2 nmol Ask for price

Mouse Hemoglobin subunit alpha, HBA GENLISA ELISA

KLM1125 1 x 96 wells
EUR 341

Canine Hemoglobin subunit alpha, HBA GENLISA ELISA

KLN0042 1 x 96 wells
EUR 341

Bovine Hemoglobin subunit alpha, HBA GENLISA ELISA

KLB0052 1 x 96 wells
EUR 341

Hba-x 3'UTR GFP Stable Cell Line

TU159377 1.0 ml Ask for price

Porcine Hemoglobin subunit alpha, HBA GENLISA ELISA

KLP0328 1 x 96 wells
EUR 341

Hba-a1 3'UTR GFP Stable Cell Line

TU159375 1.0 ml Ask for price

Hba-a2 3'UTR GFP Stable Cell Line

TU159376 1.0 ml Ask for price

The CMV-NIR status is associated with the incidence of CMV reactivation transplantation which is significantly higher, indicating that the immunity of CMV dysfunctional in prospective lung transplant recipients is associated with an increased risk of viral viral-transplant reactivation.
Keywords: cytomegalovirus; T-cell immunity; solid organ transplant; Virus reactivation.

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