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Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Mother’s infarction (MFI) and Masif Fibrin Perive (MPFD) deposition (MPFD) are unusual, related to the condition of the secondary placenta of trophoblastic cell damage. The etiology is unknown but MPFD / MFI is associated with adverse obstetric results and a significant risk of repeatment. Case Report: We report the MPFD / MFI case related to placentitis Cytomegalovirus (CMV). A 27-year-old mother gave birth to a man’s fetus born with a postmortem diagnosis of default CMV.

The placenta shows limfohistiocial villitis with isolated CMV inclusion, in combination with MFI. Villitis has an intermediary feature between unclean cmv placentitis and ethiological villitis (Vue). Conclusion: Vue is considered a reaction of an anti-fetal immune mother who resembles the refusal of allograft. We postulate that viral infections in our case may have triggered this immune response, considering that CMV antigens are known to be crossing with some human antigens, especially HLA. The next trophoblastic cell damage can then lead to MFI / MFPD.

Hemolytic uremic syndrome and atypical nephrotic syndrome associated with cytomegalovirus infection

Atypical hemolytic uremic syndrome (ahus) is a rare disease. It is produced from the disregulation of alternative complementary pathways on the cell surface which causes endothelial damage. Increasing evidence evidence, this disorder is for mutations in the complementary regulator gene or with autoantibodies to complementary factors. This mutation has incomplete penetration and variable phenotypes.

Cytomegalovirus (CMV) is endemic throughout the world, and the incidence of severe CMV disease in immunocompetent adults seems to be greater than previously thought. Ahus and nephrotic syndrome associated with CMV infection rarely occur. The identification of triggers for the manifestation of the ahus in patients who are vulnerable genetics is very important because this allows faster clinical treatment and improvement initiations. We reported a case of a man with the removal of homozygous CFHR3-1 whose initial presentation was ahus and nephrotic syndrome associated with CMV infection.

IgA binds epitop glycoprotein B and neutralizes human cytomegalovirus

Human Cytomegalovirus (HCMV) is a pathogen everywhere that has the potential for pathogens in immunosuppression individuals and pregnant women during primary infections. HCMV Envelope Glycoprotein B (GB) facilitates virus entries into all types of cells and induces strong immune responses. Epitope AD-2 is a very preserved GB Linear GB epitope and the critical target for antibodies, only 50% of seropositive individuals that make IgG antibodies to this site and the rib response has not been fully investigated.

This study aims to compare IGG and IGA responses to GB and Epitop AD-2 in individuals who are exposed to naturally and those who receive the recombinant Ajuvant GB / MF59 vaccine. Thus, seropositive individual vaccination increases the existing IGA and GB IGG levels and induces the rib response and specific IGG de Novo GB on seronegative receivers. The existing IgG response and AD-2 ribs were driven by vaccination but the response of De Novo AD-2 was not detected. Individuals exposed naturally have the dominant IgG response to GB and AD-2 compared to weaker rib responses and variables, although significant rib response to AD-2 was observed in the ASI ASI sample.

All antibodies tie the AD-2 contain a light chain of kappa while the use of a balanced capa / lambda light chain is found for those who bind to GB. The V-region matches the specific recombinant IGG AD-2 and ribs are bound to GB and AD-2 and neutralize HCMV infection in vitro. Overall, this result shows that even though the human IGG response dominates, class IGA antibodies against AD-2 are significant components of breast milk that can function to protect neonates from HCMV.

Cytomegalovirus After a kidney transplant in 2020: moving towards personalized prevention

Cytomegalovirus (CMV) – Close complications after kidney transplants remain a substantial challenge. Instead of applying a preventive strategy to all risky patients, we can now adjust our strategies at the individual patient level. The prophylaxis of antivirus or strict pre-emptive strategies may be optimal for patients with the highest risk for CMV, while lower risk patients can be profitable especially from pre-emptive monitoring and therapeutic administration only if needed.

CMV Special T-Testing may be useful to improve the determination of CMV risk in pre-transplants, and to guide decisions about the need for antivirus therapy or duration. Immunosupressive regimens including the target of the Rapamycin mammal inhibitor reduces the risk of CMV and thus can be an interesting choice in some patients. The new antivirus agent further expanded our therapy arsenal in the near future, and the prospect of CMV vaccination and remove cell therapy seems to be on the horizon.

Combined Placental Maternal Floor Infarction and Cytomegalovirus Placentitis: A Case Report

Cytomegalovirus Pre-Transplant Immunity and Risk of Viral Reactivation After Lung Transplantation: Prospective Cohort Study

Cytomegalovirus (CMV) remains a significant burden on the recipient of the lung transplant. Disadvantages in the immunity of the TP-transplant increases the risk of complications related to CMV. However, it is not clear if the underlying pre-transplant immunity increases risk. To assess this, we recruit 39 lung transplant patients and do quantiferon-CMV in their peripheral blood. More than a third of prospective cmv-seropositive transplant receivers are non-imun-reactive CMV (CMV-NIR) pre-transplant.

SARS-CoV-2 Spike S1 RBD Protein, Mouse Fc-fusion
E80026
  • EUR 588.50
  • EUR 823.90
  • 20 ul
  • 50 ul

SARS-CoV-2 Spike S1 (16-685) Protein, Avi-His-tag
E80021
  • EUR 635.80
  • EUR 4276.80
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 RBD (V367F) Protein, Avi-His-tag
E80023
  • EUR 635.80
  • EUR 3934.70
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 (13-665) Protein, Fc Fusion, Avi-tag
E80020
  • EUR 635.80
  • EUR 4276.80
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 (16-685) Protein, Fc Fusion, Avi-tag
E80022
  • EUR 635.80
  • EUR 4276.80
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 RBD Protein, Human Fc-Fusion, Avi-Tag
E80025
  • EUR 635.80
  • EUR 3934.70
  • 100 ul
  • 1 ml

Recombinant Transmembrane Protease Serine 2 Protein, Partial
E80016
  • EUR 470.80
  • EUR 753.50
  • EUR 1824.90
  • 20 ul
  • 100 ul
  • 500 ul

HBA Polyclonal Antibody
ABP58750-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

HBA Polyclonal Antibody
ABP58750-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

HBA Polyclonal Antibody
ABP58750-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of HBA from Human, Mouse, Rat. This HBA antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human HBA protein at amino acid sequence of 30-110

HBA Polyclonal Antibody
ES11261-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against HBA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

HBA Polyclonal Antibody
ES11261-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against HBA from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

Anti-HBA antibody
STJ192419 200 µl
EUR 236.4
Description: Unconjugated Rabbit polyclonal to HBA

Hba Polyclonal Antibody
A53679-020 20 ul Ask for price

Hba Polyclonal Antibody
A53679-050 50 ul Ask for price

Hba Polyclonal Antibody
A53679-100 100 ul
EUR 423.5

Hba Polyclonal Antibody
A53679
  • EUR 684.66
  • Ask for price
  • Ask for price
  • EUR 423.50
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

Hba Antibody, HRP conjugated
1-CSB-PA010147LB01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is HRP conjugated. Tested in the following application: ELISA

Hba Antibody, FITC conjugated
1-CSB-PA010147LC01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA

Hba Antibody, Biotin conjugated
1-CSB-PA010147LD01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Hba. Recognizes Hba from Mouse. This antibody is Biotin conjugated. Tested in the following application: ELISA

Human Brain Astrocytes (HBA)
HMP202 500,000+ cells - Frozen
EUR 1296

ACE2, His-Tag Protein
E80019
  • EUR 612.70
  • EUR 1437.70
  • 20 ul
  • 100 ul

Hba-a2 sgRNA CRISPR Lentivector (Rat) (Target 2)
K6915803 1.0 ug DNA
EUR 184.8

Hba-a2 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K3179403 1.0 ug DNA
EUR 184.8

Hba-x sgRNA CRISPR Lentivector (Mouse) (Target 2)
K3266403 1.0 ug DNA
EUR 184.8

Hba-a1 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K3332403 1.0 ug DNA
EUR 184.8

Hemoglobin Subunit Alpha (Hba) Antibody
20-abx109857
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mouse Hemoglobin subunit alpha (Hba)
1-CSB-EP010147MO
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Hemoglobin subunit alpha(Hba) expressed in E.coli

Mouse Hemoglobin subunit alpha (Hba)
1-CSB-YP010147MO
  • EUR 604.80
  • EUR 318.00
  • EUR 2198.40
  • EUR 915.60
  • EUR 1459.20
  • EUR 400.80
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Hemoglobin subunit alpha(Hba) expressed in Yeast

HBA ELISA Kit (Mouse) (OKEH05810)
OKEH05810 96 Wells
EUR 794.4
Description: Description of target: Involved in oxygen transport from the lung to the various peripheral tissues. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.84 ng/mL

HBA ELISA Kit (Bovine) (OKEH03848)
OKEH03848 96 Wells
EUR 934.8
Description: Description of target: Involved in oxygen transport from the lung to the various peripheral tissues.;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.59 ng/mL

Hba-a2 Recombinant Protein (Rat)
RP204248 100 ug Ask for price

Hba-a1 Recombinant Protein (Mouse)
RP140990 100 ug Ask for price

Hba-a2 Recombinant Protein (Mouse)
RP140993 100 ug Ask for price

Hba-x Recombinant Protein (Mouse)
RP140996 100 ug Ask for price

Hba Polyclonal Antibody, HRP Conjugated
A53680-050 50 ul
EUR 302.5

Hba Polyclonal Antibody, HRP Conjugated
A53680-100 100 ul
EUR 423.5

Hba Polyclonal Antibody, FITC Conjugated
A53681-050 50 ul
EUR 302.5

Hba Polyclonal Antibody, FITC Conjugated
A53681-100 100 ul
EUR 423.5

Hba Polyclonal Antibody, Biotin Conjugated
A53682-050 50 ul
EUR 302.5

Hba Polyclonal Antibody, Biotin Conjugated
A53682-100 100 ul
EUR 423.5

Hba Polyclonal Antibody, HRP Conjugated
A53680
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Hba Polyclonal Antibody, FITC Conjugated
A53681
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Hba Polyclonal Antibody, Biotin Conjugated
A53682
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Rat Hemoglobin subunit alpha-1/2, HBA ELISA Kit
ELA-E0517r 96 Tests
EUR 1063.2

Human Anti-Influenza B virus IgA ELISA kit, 96 tests, Quantitative
920-410-HBA 1 Kit
EUR 854.4

Hba-a2 ORF Vector (Rat) (pORF)
ORF068084 1.0 ug DNA
EUR 607.2

Hba-a1 ORF Vector (Mouse) (pORF)
ORF046998 1.0 ug DNA
EUR 607.2

Hba-a2 ORF Vector (Mouse) (pORF)
ORF046999 1.0 ug DNA
EUR 607.2

Hba-x ORF Vector (Mouse) (pORF)
ORF047000 1.0 ug DNA
EUR 607.2

Recombinant TMPRSS2 Protein, Partial
E80017
  • EUR 423.50
  • EUR 660.00
  • EUR 2321.00
  • 20 ul
  • 100 ul
  • 1 ml

Recombinant Novel Coronavirus Spike Glycoprotein(S), Partial
E80018
  • EUR 388.30
  • EUR 860.20
  • EUR 4888.40
  • 20 ul
  • 100 ul
  • 1 ml

Nori® Human Angiopoietin-2 (ANG-2) ELISA Kit (2 plates)
GR106245-2 2 x 96-well
EUR 998.4

Nori Equine MMP-2/TIMP-2 Complex ELISA Kit (2 plates)
GR106502-2 2 x 96-well
EUR 998.4

2-Propyl-β-D-glucuronide, 2 mg
0904-2 2 mg
EUR 194.4

Bovine HBA/ Hemoglobin subunit alpha ELISA Kit
E0304Bo 1 Kit
EUR 860.4

Hba-a2 sgRNA CRISPR Lentivector set (Rat)
K6915801 3 x 1.0 ug
EUR 406.8

Human Hemoglobin subunit alpha, HBA ELISA Kit
ELA-E05171h 96 Tests
EUR 988.8

Bovine Hemoglobin subunit alpha, HBA ELISA Kit
ELA-E0517b 96 Tests
EUR 1113.6

Chicken Hemoglobin subunit alpha, HBA ELISA Kit
ELA-E0517c 96 Tests
EUR 1113.6

Canine Hemoglobin subunit alpha, HBA ELISA Kit
ELA-E0517d 96 Tests
EUR 1113.6

Mouse Hemoglobin subunit alpha, HBA ELISA Kit
ELA-E0517m 96 Tests
EUR 1038

Porcine Hemoglobin subunit alpha, HBA ELISA Kit
ELA-E0517p 96 Tests
EUR 1113.6

Hba-a2 sgRNA CRISPR Lentivector set (Mouse)
K3179401 3 x 1.0 ug
EUR 406.8

Hba-x sgRNA CRISPR Lentivector set (Mouse)
K3266401 3 x 1.0 ug
EUR 406.8

Hba-a1 sgRNA CRISPR Lentivector set (Mouse)
K3332401 3 x 1.0 ug
EUR 406.8

Nori® Human MMP-2/TIMP-2 Complex ELISA Kit (2 plates)
GR106372-2 2 x 96-well
EUR 998.4

Nori® Human b-defensin 2 (BD-2) ELISA Kit- 2 Plates
GR111099-2 2 x 96-well
EUR 998.4

Nori Equine MMP-2 ELISA Kit-2 Plates
GR106478-2 2 x 96-well
EUR 998.4

Nori Equine TIM-2 ELISA Kit (2 plates)
GR106516-2 2 x 96-well
EUR 998.4

Nori Human TIM-2 ELISA Kit-2 Plates
GR111039-2 2 x 96-well
EUR 998.4

Nori Canine TIM-2 ELISA Kit (2 plates)
GR115041-2 2 x 96-well
EUR 998.4

2 M NaCl
GR103063-2 200 mL
EUR 70.8

Hba-a2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
K6915807 1.0 ug DNA
EUR 200.4

Hba-a2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K3179407 1.0 ug DNA
EUR 200.4

Hba-x sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K3266407 1.0 ug DNA
EUR 200.4

Hba-a1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K3332407 1.0 ug DNA
EUR 200.4

Nori® Chicken Netrin-2 ELISA Kit (2 plates)
GR106184-2 2 x 96-well
EUR 998.4

Nori® Human Tie-2 ELISA Kit (2 plates)
GR106458-2 2 x 96-well
EUR 998.4

Nori® Human TIMP-2 ELISA Kit (2 plates)
GR106460-2 2 x 96-well
EUR 998.4

Nori® Human Trappin-2 ELISA Kit (2 plates)
GR106467-2 2 x 96-well
EUR 998.4

Nori® Mouse IL-2 ELISA Kit- 2 Plates
GR117024-2 2 x 96-well
EUR 998.4

Nori® Mouse IGFBP-2 ELISA Kit- 2 Plates
GR117043-2 2 x 96-well
EUR 998.4

Nori® Rabbit IL-2 ELISA Kit- 2 Plates
GR144032-2 2 x 96-well
EUR 998.4

Nori® Monkey IL-2 ELISA Kit- 2 Plates
GR169004-2 2 x 96-well
EUR 998.4

Nori® Donkey IL-2 ELISA Kit- 2 Plates
GR170004-2 2 x 96-well
EUR 998.4

Nori® Porcine MMP-2 ELISA Kit- 2 Plates
GR113006-2 2 x 96-well
EUR 998.4

Nori® Chicken MMP-2 ELISA Kit- 2 Plates
GR114008-2 2 x 96-well
EUR 998.4

Nori® Chicken IGFBP-2 ELISA Kit-2 Plates
GR114026-2 2 x 96-well
EUR 998.4

IL-2 Interleukin-2 Human Recombinant Protein, His Tag
PROTP60568-2 Regular: 10ug
EUR 380.4
Description: Interleukin-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 133 amino acids fragment (21-153) having a molecular weight of 20kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. _x000D_ The IL-2 His is purified by proprietary chromatographic techniques._x000D_

Nori® Canine (dog) IL-2 ELISA Kit (2 plates)
GR106163-2 2 x 96-well
EUR 998.4

Nori® Porcine (pig) IL-2 ELISA Kit (2 plates)
GR106188-2 2 x 96-well
EUR 998.4

Nori® Guinea Pig IL-2 ELISA Kit- 2 Plates
GR171004-2 2 x 96-well
EUR 998.4

Nori® Porcine b-defensin 2 ELISA Kit- 2 Plates
GR113081-2 2 x 96-well
EUR 998.4

BMP-2 Bone Morphogenetic Protein-2 Human Recombinant Protein, Monomer
PROTP12643-2 Regular: 20ug
EUR 380.4
Description: Bone Morphogenetic Protein-2 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, Polypeptide chain containing 115 amino acids (283-396) and having a molecular mass of 13009 Dalton. ;The BMP-2 is purified by proprietary chromatographic techniques.

PG LIVER 2 EA*
59423-2 2 EA
EUR 230.69

Individual Reaction Mix 2
G065-2 200 reactions
EUR 200.4

2-Chloroethyl vinyl ether
2-CLVIN 1ML
EUR 26.22

Organic Wine Standard 2
WINE-2 1ML
EUR 100.32

Methylamp DNA Modification Kit 
P-1001
  • EUR 416.70
  • EUR 149.60
  • EUR 259.60
  • 80 Reactions
  • 40 Reactions
  • 80 Reactions

FitAmp General Tissue Section DNA Isolation Kit 
P-1003
  • EUR 754.26
  • EUR 253.00
  • EUR 490.60
  • 100 Samples
  • 50 Samples
  • 100 Samples

FitAmp Plasma/Serum DNA Isolation Kit 
P-1004
  • EUR 416.70
  • EUR 149.60
  • EUR 253.00
  • 100 Samples
  • 50 Samples
  • 100 Samples

TuMinute PCR Clean-Up Kit 
P-1005
  • EUR 303.60
  • EUR 90.20
  • EUR 171.60
  • 100 Samples
  • 50 Samples
  • 100 Samples

DNA Concentrator Kit 
P-1006
  • EUR 303.60
  • EUR 90.20
  • EUR 171.60
  • 100 Samples
  • 50 Samples
  • 100 Samples

FitAmp Paraffin Tissue Section DNA Isolation Kit 
P-1009
  • EUR 702.06
  • EUR 239.80
  • EUR 454.30
  • 100 Samples
  • 50 Samples
  • 100 Samples

Methylamp One-Step DNA Modification Kit 
P-1010
  • EUR 416.70
  • EUR 148.50
  • EUR 253.00
  • 80 Samples
  • 40 Samples
  • 80 Samples

Methylamp Universal Methylated DNA Kit 
P-1011
  • EUR 684.66
  • EUR 292.60
  • EUR 442.20
  • 20 Modifications
  • 10 Modifications
  • 20 Modifications

FitAmp Circulating DNA Quantification Kit 
P-1012
  • EUR 595.92
  • EUR 217.80
  • EUR 387.20
  • 96 Assays
  • 48 Assays
  • 96 Assays 

EpiQuik DNA Methyltransferase (DNMT) Activity/Inhibition Assay Kit 
P-3001
  • EUR 1050.06
  • EUR 424.60
  • EUR 712.80
  • 96 Assays
  • 48 Assays
  • 96 Assays

EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K4) 
P-3002
  • EUR 1067.46
  • EUR 437.80
  • EUR 724.90
  • 96 Assays
  • 48 Assays
  • 96 Assays

EpiQuik Histone Methyltransferase Activity/Inhibition Assay Kit (H3K9) 
P-3003
  • EUR 1067.46
  • EUR 437.80
  • EUR 724.90
  • 96 Assays
  • 48 Assays
  • 96 Assays

The CMV-NIR status is associated with the incidence of CMV reactivation transplantation which is significantly higher, indicating that the immunity of CMV dysfunctional in prospective lung transplant recipients is associated with an increased risk of viral viral-transplant reactivation.
Keywords: cytomegalovirus; T-cell immunity; solid organ transplant; Virus reactivation.

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