Association of human cytomegalovirus (HCMV) neutralizing antibodies with antibodies to the HCMV glycoprotein complexes

Association of human cytomegalovirus (HCMV) neutralizing antibodies with antibodies to the HCMV glycoprotein complexes

Background: Human cytomegalovirus (HCMV) causes no symptoms, but also cause congenital infection when HCMV-infected women during pregnancy, and life-threatening disease in immunocompromised patients. To better understand the mechanism of neutralization activity against HCMV, HCMV antibody titers association NT judged by antibody titers against each glycoprotein complex (gc) of HCMV.


Methods: Sera were collected from 78 healthy adult volunteers were used. Merlin HCMV HCMV clinical isolates strain and 1612 strain used in the NT test with plaque reduction test, in which both the MRC-5 fibroblasts cells and RPE-1 epithelial cells are used. Complex glycoprotein gB, gH / gL complex (gH / gL / GO and gH / gL / UL128-131A [PC]) and GM / GN selected as the target glycoprotein. 293FT cells expressed with gB, GM / gn, gH / gL / GO, or PC, is prepared and used for the measurement of antibody titers against each gc in an indirect immunofluorescence assay (IIFA). The correlation between titer IIFA for every gc and HCMV-NT titers evaluated.


Results: No significant correlation between specific titer IIFA gB and HCMV-NT titers in the epithelial cells or between GM / GN specific complex titer and titer IIFA HCMV-NT. On the other hand, there is a positive correlation statistically significant between the titer IIFA for complex gH / gL and the titer of HCMV-NT.

Conclusion: The data show that the complex of gH / gL may be a prime target for inducing activity against HCMV NT.

 Association of human cytomegalovirus (HCMV) neutralizing antibodies with antibodies to the HCMV glycoprotein complexes
Association of human cytomegalovirus (HCMV) neutralizing antibodies with antibodies to the HCMV glycoprotein complexes

Based Necroptosis CRISPR screen Neuropilin-1 knockout revealed as the host factors important for the early stages of murine cytomegalovirus infection

The herpes virus is a human pathogen everywhere which causes various health complications. Currently, there is an incomplete understanding of the cellular factors that contribute to the herpes virus infection. Here, we report the antivirus necroptosis based genetic screen to identify factors of new host cells is required for β-herpes virus infection of murine cytomegalovirus (MCMV).

screen-based genome-wide CRISPR we utilized the capacity of the mutant herpes virus that triggers cell death necroptotic antivirus virus early gene expression. Vascular endothelial growth factor (VEGF) and semaphorin receptor binding Neuropilin-1 (Nrp-1) has emerged as an important determinant of MCMV infection. We found that the removal of damage early Nrp-1 virus gene expression and reduce the rate of infection in endothelial cells, fibroblasts and macrophages. Furthermore, preincubation with soluble Nrp virus-1 infection by reducing dramatically inhibit virus attachment. Thus, Nrp-1 is a major determinant of the initial phase of MCMV infection.

p38 Antibody

48644-100ul 100ul
EUR 399.6

p38 Antibody

48644-50ul 50ul
EUR 286.8

p38 Antibody

E38PA3186 100ul
EUR 225
Description: Available in various conjugation types.

p38 Antibody

E38PA7126 100ul
EUR 225
Description: Available in various conjugation types.

p38 Antibody

E38PA4721 100ul
EUR 225
Description: Available in various conjugation types.

p38 Antibody

E38PA5060 100ul
EUR 225
Description: Available in various conjugation types.

p38 Antibody

E38PA5094 100ul
EUR 225
Description: Available in various conjugation types.

p38 antibody

70R-51505 100 ul
EUR 242
Description: Purified Polyclonal p38 antibody

p38 antibody

70R-51506 100 ul
EUR 286
Description: Purified Polyclonal p38 antibody

p38 Antibody

abx236076-100ug 100 ug
EUR 577.2

p38 Antibody

20-abx141038
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p38 Antibody

20-abx133223
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p38 Antibody

20-abx007541
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p38 Antibody

abx236076-100g 100 µg
EUR 350

SB-203580 p38 MAPK(p38 MAP kinase) Inhibitor

E1B1863 1mg
EUR 85

p38 Mouse mAb

E2220879 100ul
EUR 225
Description: Available in various conjugation types.

p38 Mouse mAb

E2222580 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

p38 Rabbit pAb

E2340697 100ul
EUR 225
Description: Available in various conjugation types.

p38 Rabbit pAb

E2380881 100ul
EUR 225
Description: Available in various conjugation types.

p38 Rabbit pAb

E2381051 100ul
EUR 225
Description: Available in various conjugation types.

p38 Rabbit pAb

E2251338 100ul
EUR 225
Description: Available in various conjugation types.

p38 Rabbit pAb

E2251719 100ul
EUR 225
Description: Available in various conjugation types.

p38 Rabbit mAb

E2R25239 100μl
EUR 225
Description: Available in various conjugation types.

p38 Rabbit mAb

E2R27123 100μl
EUR 225
Description: Available in various conjugation types.

anti-Crk p38

YF-PA11088 50 ul
EUR 435.6
Description: Mouse polyclonal to Crk p38

anti-Crk p38

YF-PA11089 50 ug
EUR 435.6
Description: Mouse polyclonal to Crk p38

anti-Crk p38

YF-PA11090 100 ug
EUR 483.6
Description: Rabbit polyclonal to Crk p38

anti-Crk p38

YF-PA23509 50 ul
EUR 400.8
Description: Mouse polyclonal to Crk p38

p38 beta, Active

7763-100 each
EUR 5214

p38 beta, Active

7763-5 each
EUR 444

p38 beta protein

30R-2875 5 ug
EUR 425
Description: Purified recombinant Human p38 beta protein

Crk p38 Antibody

AF6323 200ul
EUR 420

Crk p38 Antibody

AF6323-100ul 100ul
EUR 280

Crk p38 Antibody

AF6323-200ul 200ul
EUR 350

Crk Antibody p38

R31526 100 ug
EUR 356.15
Description: CRK, also known as p38, is a protein that in humans is encoded by the CRK gene. This gene is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It is mapped to 17p13.3. The protein participates in the Reelin signaling cascade downstream of DAB1. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of Crk functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

anti-AIMP2/p38

YF-PA15507 50 ug
EUR 435.6
Description: Mouse polyclonal to AIMP2/p38

p38 Hog Antibody

P9809 100ug
EUR 259

p38 MAPK antibody

10R-8422 100 ul
EUR 471.6
Description: Mouse monoclonal p38 MAPK antibody

p38 MAPK antibody

20R-1572 100 ug
EUR 846
Description: Rabbit polyclonal p38 MAPK antibody

P38 MAPK antibody

20R-2087 50 ug
EUR 269
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

20R-2088 50 ug
EUR 269
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

20R-2403 50 ug
EUR 269
Description: Rabbit polyclonal P38 MAPK antibody

p38 MAPK antibody

20R-2950 100 ul
EUR 471.6
Description: Rabbit polyclonal p38 MAPK antibody

P38 delta protein

30R-2868 5 ug
EUR 425
Description: Purified recombinant Human P38 delta protein

p38 alpha protein

30R-2870 5 ug
EUR 425
Description: Purified recombinant Human p38 alpha protein

p38 MAPK Antibody

E18-6456-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

p38 MAPK Antibody

E18-6456-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

p38 MAPK Antibody

E2310008 100ug
EUR 225
Description: Available in various conjugation types.

p38 MAPK Antibody

AF6455 200ul
EUR 420

p38 MAPK Antibody

AF6455-100ul 100ul
EUR 280

p38 MAPK Antibody

AF6455-200ul 200ul
EUR 350

p38 MAPK Antibody

AF6456 200ul
EUR 420

p38 MAPK Antibody

AF6456-100ul 100ul
EUR 280

p38 MAPK Antibody

AF6456-200ul 200ul
EUR 350

p38 MAPK Antibody

AF6457 200ul
EUR 420

p38 MAPK Antibody

AF6457-100ul 100ul
EUR 280

p38 MAPK Antibody

AF6457-200ul 200ul
EUR 350

p38 MAPK Antibody

49379 100ul
EUR 499

p38 MAPK Antibody

49379-100ul 100ul
EUR 399.6

p38 MAPK Antibody

49379-50ul 50ul
EUR 286.8

p38 MAPK antibody

70R-33398 100 ug
EUR 294
Description: Rabbit polyclonal p38 MAPK antibody

p38 MAPK antibody

70R-33400 100 ug
EUR 294
Description: Rabbit polyclonal p38 MAPK antibody

P38 MAPK antibody

70R-34325 100 ug
EUR 294
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

70R-34327 100 ug
EUR 294
Description: Rabbit polyclonal P38 MAPK antibody

p38 MAPK Antibody

abx236077-100ug 100 ug
EUR 577.2

p38 MAPK Antibody

20-abx012798
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p38 MAPK Antibody

20-abx012875
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p38 MAPK Antibody

ABF6456 100 ug
EUR 525.6

anti- p38 antibody

FNab06076 100µg
EUR 606.3
Description: Antibody raised against p38

p38 MAPK Antibody

R20266-0.1ML 100ul
EUR 347.65
Description: This recombinant p38 antibody reacts to human p38 MAPK. It may also react to the rat and mouse protein, as predicted by immunogen homology.

p38 (pT180) Antibody

E38PA3187 100ul
EUR 225
Description: Available in various conjugation types.

p38 (pY323) Antibody

E38PA4458 100ul
EUR 225
Description: Available in various conjugation types.

AIMP2/p38 Antibody

DF12048 200ul
EUR 420

AIMP2/p38 Antibody

DF12048-100ul 100ul
EUR 280

AIMP2/p38 Antibody

DF12048-200ul 200ul
EUR 350

p38 (pY182) Antibody

E38PA7040 100ul
EUR 225
Description: Available in various conjugation types.

p38 (pY182) Antibody

20-abx134951
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  • 100 ul
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p38 (pY323) Antibody

20-abx133058
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  • 100 ul
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p38 (pT180) Antibody

20-abx009863
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p38 MAPK Inhibitor

T36010-10mg 10mg Ask for price
Description: p38 MAPK Inhibitor

p38 MAPK Inhibitor

T36010-1g 1g Ask for price
Description: p38 MAPK Inhibitor

p38 MAPK Inhibitor

T36010-1mg 1mg Ask for price
Description: p38 MAPK Inhibitor

p38 MAPK Inhibitor

T36010-50mg 50mg Ask for price
Description: p38 MAPK Inhibitor

p38 MAPK Inhibitor

T36010-5mg 5mg Ask for price
Description: p38 MAPK Inhibitor

p38 alpha-MAPK14

RA15053 100 ug
EUR 631.2

p38 Antibody (MAPK14)

F50496-0.08ML 0.08 ml
EUR 140.25
Description: P38 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

p38 Antibody (MAPK14)

F50496-0.4ML 0.4 ml
EUR 322.15
Description: P38 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

p38 Blocking Peptide

20-abx061736
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  • 1 mg
  • 5 mg

p38 Blocking Peptide

20-abx062080
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  • 1 mg
  • 5 mg

p38 Blocking Peptide

20-abx161932
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  • 1 mg
  • 5 mg

Human p38 MAPK alpha ,pT180/Y182(p38 MAPKP) Elisa Kit

EK715654 96 Wells
EUR 0.51

p38 Polyclonal Antibody

41305-100ul 100ul
EUR 302.4

p38 Polyclonal Antibody

41305-50ul 50ul
EUR 224.4

p38 Polyclonal Antibody

41306 100ul
EUR 319

p38 Polyclonal Antibody

41306-100ul 100ul
EUR 302.4

p38 Polyclonal Antibody

41306-50ul 50ul
EUR 224.4

p38 Polyclonal Antibody

E041305 100μg/100μl
EUR 255
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E041306 100μg/100μl
EUR 255
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E20-73511 100ug
EUR 225
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E20-73512 100ug
EUR 225
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E20-73513 100ug
EUR 225
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E20-73514 100ug
EUR 225
Description: Available in various conjugation types.

p38 Polyclonal Antibody

E20-75662 100ug
EUR 225
Description: Available in various conjugation types.

p38 Polyclonal Antibody

ABP53838-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53838-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53838-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53839-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP53839-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP53839-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP52112-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52112-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52112-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52113-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP52113-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP52113-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP57354-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody

ABP57354-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody

ABP57354-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody

ABP0150-100uL 100 μL
EUR 229
Description: Rabbit Anti-p38 Polyclonal Antibody

p38 Polyclonal Antibody

E44H07104 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

p38 Polyclonal Antibody

E44H02702 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

p38 Polyclonal Antibody

E44H02703 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

p38 Polyclonal Antibody

E44H02704 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

p38 Polyclonal Antibody

E44H02705 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

P38 Polyclonal Antibody

E-AB-70001-120uL 120uL
EUR 260
Description: Unconjugated

P38 Polyclonal Antibody

E-AB-70001-200uL 200uL
EUR 410
Description: Unconjugated

P38 Polyclonal Antibody

E-AB-70001-60uL 60uL
EUR 160
Description: Unconjugated

P38 Polyclonal Antibody

E-AB-70001-each each Ask for price
Description: Unconjugated

P38 Monoclonal Antibody

E-AB-22147-120uL 120uL
EUR 240
Description: Unconjugated


Cytomegalovirus (CMV) is a ubiquitous virus that infects people around the world. CMV is known to trigger thrombocytopenia, but the relationship is probably underdiagnosed since CMV infection in healthy adults usually either asymptomatic or cause mild symptoms. A systematic literature review conducted and produced 23 publications that reported in 25 patients. All hematology centers in Israel were searched for adult immunocompetent patients with CMV-related thrombocytopenia, and five new cases were identified. The average age of the combined 30 patients was 33 years (range 18-80), 73% were male, 77% presented with CMV-related symptoms, 48% had an enlarged spleen, 95% had atypical lymphocytes in the peripheral blood and 68% have increased transaminase levels.

The response rate for the first-line regimen containing steroids only 31%, while 11 patients were treated with anti-CMV agents have a response rate of 82%. In addition, four patients received receptor agonist thrombopoietin (TPO-RA) are three (75%) responded. Taken together, a typical feature of cases with thrombocytopenia must guard against CMV infection as the source.

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